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Genmab — Juni 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • K Offline
    K Offline
    kkjoel
    wrote on sidst redigeret af
    #596

    Så det har nok været vigtigt for GEN at lave en "ny" teknologiaftale. Siden der ingen upfront er.

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    • B Offline
      B Offline
      Bella1
      wrote on sidst redigeret af
      #597

      Satans krystalkugle! 🙂

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #598

        You have to take this deal in relation to the current Dara deal; i am pretty certain Genmab is not allowed to create a CD38 for MM under the current Dara contract with JNJ.

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        • SolsenS Offline
          SolsenS Offline
          Solsen
          wrote on sidst redigeret af
          #599

          Det kunne også ligge i at CD38 er lukket land for Genmab pga JNJ aftalen omkring Darzalex. Nu får Genmab muligheden for at forlænge royaltystrømmen med et nyt produkt.

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          • SolsenS Offline
            SolsenS Offline
            Solsen
            wrote on sidst redigeret af
            #600

            🙂

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #601

              Had they been allowed to develop it with another partner, this deal might have looked very very different

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #602

                lol @Solsen

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #603

                  same thoughts

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                  • K Offline
                    K Offline
                    kkjoel
                    wrote on sidst redigeret af
                    #604

                    Jeps.. forlængelse af royaltystrømme giver absolut rigtig god strategisk mening.

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                    • J Offline
                      J Offline
                      JKY_VH
                      wrote on sidst redigeret af
                      #605

                      Har nogen hørt noget fra Novod? Hans udlægning af "Genmabs tilstand", har før vist sig at være retningsgivende.

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                      • M Offline
                        M Offline
                        mobbyduck1
                        wrote on sidst redigeret af
                        #606

                        han er sikkert stadig fornærmet

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                        • L Offline
                          L Offline
                          lahn1
                          wrote on sidst redigeret af
                          #607

                          Syntes at sidste sætning i 1. afsnit antyder at GEN reelt ikke har kunne bruge HBCD38 selv pga restriktioner i DAR aftalen med JNJ, derfor denne gratis aftale. JNJ siger "vis at det virker" og så vil vi gerne betale lidt for det. Eller kan GEN parkere HBCD38 i kælderen ?

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                          • J Offline
                            J Offline
                            JKY_VH
                            wrote on sidst redigeret af
                            #608

                            Tjah, nu må snart kravle ned af træet igen:-)

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                            • J Offline
                              J Offline
                              JKY_VH
                              wrote on sidst redigeret af
                              #609

                              han

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #610

                                @lahn1 we are only talking development costs now so far; once JNJ triggers the option to co-develop, they will start sharing the cost. And that is when i gets expensive, think of the large trials they have been doing with Dara

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                                • S Offline
                                  S Offline
                                  Sibelius
                                  wrote on sidst redigeret af
                                  #611

                                  Det er også en "get-out of jail" aftale idet at hvis JNJ ikke vil udnytte optionen (og midlet virker" er Genmab frit stillet til selv at markedsføre

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                                  • DarvinD Offline
                                    DarvinD Offline
                                    Darvin
                                    wrote on sidst redigeret af
                                    #612

                                    Som jeg læser teksten er de langt. De har gode prekliniske data og som de skriver could be superior to daratumumab for certain tumor cell types. Måske ikke langt fra at de er klar til næste skridt.

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #613

                                      @E L: I think it's developing, not co-developing. If Janssen exercises the option they'll take over all the costs - as I see it.

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #614

                                        oh really, i read that wrong then; that is a BIG difference!

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #615

                                          think you are correct. makes sense also really, given the current Dara deal, they are extending and improving that

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