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Genmab — Juni 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #475

    Tx. it's a bit strange that ixazomib doesn't work in amy as bortezomib apparantly works well with dara. Maybe some kind of synergi (again).

    1 Reply Last reply
    0
    • K Offline
      K Offline
      kkjoel
      wrote on sidst redigeret af
      #476

      3000 nye pt om året i US - hvor meget kan det mon generere i oms?

      1 Reply Last reply
      0
      • BulderB Offline
        BulderB Offline
        Bulder
        wrote on sidst redigeret af
        #477

        Vi har talt om det før og nåede vist frem til at amy og MDS tilsammen er det halve af MM.

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        • BulderB Offline
          BulderB Offline
          Bulder
          wrote on sidst redigeret af
          #478

          Amyloidosis foundation siger 4500 nye tilfælde pr år. American cancer society siger 32.000 nye MM tilælde hvert år. http://amyloidosis.org/facts/al/ https://www.cancer.org/cancer/multiple-myeloma/about/key-statistics.html

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          0
          • BulderB Offline
            BulderB Offline
            Bulder
            wrote on sidst redigeret af
            #479

            Hvis fordelingen er den samme på verdensplan og hvis dara kan peake med 8 mia $ i MM, vil amy kunne indbringe 1-1½ Mia $.

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            0
            • BulderB Offline
              BulderB Offline
              Bulder
              wrote on sidst redigeret af
              #480

              MDS er betydeligt større. Mere end 10.000 nye tilfælde i US om året. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394456/

              1 Reply Last reply
              0
              • K Offline
                K Offline
                kkjoel
                wrote on sidst redigeret af
                #481

                Og har vi en god idé om størrelsesordenen af GENs royalty.. er det 20%, 12% eller mindre? Eller måske bare som i MM?

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                0
                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #482

                  Royaltyen er den samme

                  1 Reply Last reply
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                  • SolsenS Offline
                    SolsenS Offline
                    Solsen
                    wrote on sidst redigeret af
                    #483

                    Alle bidrag er velkommen 😉

                    1 Reply Last reply
                    0
                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #484

                      Det kan sagtens gå hen og løbe op. Især hvis dara også har effekt i CLL og AML. Og tænk hvis sc dara tager revanche i solide. Jamen hvad ender det så ikke med. 🙂

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                      0
                      • SolsenS Offline
                        SolsenS Offline
                        Solsen
                        wrote on sidst redigeret af
                        #485

                        $20bn som JW faktisk har indikeret ved at sige at JNJ ventede at tjene $10bn årligt ved peaksale.

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                        0
                        • SolsenS Offline
                          SolsenS Offline
                          Solsen
                          wrote on sidst redigeret af
                          #486

                          De 12000 pts jeg nævnte var dem der pt er i US. Så en stor pulje at starte på.

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                          0
                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #487

                            grant 6,464 restricted stock units and 21,343 warrants . just a few more as last year.

                            1 Reply Last reply
                            0
                            • B Offline
                              B Offline
                              bibob
                              wrote on sidst redigeret af
                              #488

                              God morgen. :-). https://www.fiercebiotech.com/research/stopping-cancer-before-it-develops?mkt_tok=eyJpIjoiTnpsbVlUWm1NV015TlRoaiIsInQiOiJ0M3Q2VFVsRWhReU9KOHp1K255ZFFcLzRGckRySVdMQ25SRUhmYXNtcHpqNmFOYVlqYmdWV3FqNW5SKys0TFdOZEZDMmJVb2VEazVXQzF1R2VIdTBUTU5YT01hbzBUT1NHQ3RnQlNLRmw5a3oxMyt0bzhQbHNBNElLS2Z3MFVxXC81In0%3D&mrkid=41140432

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                              0
                              • S Offline
                                S Offline
                                Sukkeralf
                                wrote on sidst redigeret af
                                #489

                                Just a moment...

                                favicon

                                (www.firstwordpharma.com)

                                1 Reply Last reply
                                0
                                • Helge_LarsenPI-redaktørH Offline
                                  Helge_LarsenPI-redaktørH Offline
                                  Helge_LarsenPI-redaktør
                                  wrote on sidst redigeret af
                                  #490

                                  God morgen. 🙂

                                  1 Reply Last reply
                                  0
                                  • P Offline
                                    P Offline
                                    Parasitism
                                    wrote on sidst redigeret af
                                    #491

                                    God morgen 🙂

                                    1 Reply Last reply
                                    0
                                    • P Offline
                                      P Offline
                                      polle1
                                      wrote on sidst redigeret af
                                      #492

                                      God morgen og god dag 🙂

                                      1 Reply Last reply
                                      0
                                      • L Offline
                                        L Offline
                                        lahn1
                                        wrote on sidst redigeret af
                                        #493

                                        @EL - I believe GEN is/have been buying back stocks to cover these, right ?

                                        1 Reply Last reply
                                        0
                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #494

                                          they definately do for the restricted stock units, i can't remember how they hedge the warrants, but i think they have anti dilution measures in place there also

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                                          0

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