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Genmab — April 2019

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • J Offline
    J Offline
    JKY_VH
    wrote on sidst redigeret af
    #392

    tak E L

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    • P Offline
      P Offline
      peter12
      wrote on sidst redigeret af
      #393

      AQR har reduceret til 1,88% dvs 0,11% ?

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      • P Offline
        P Offline
        peter12
        wrote on sidst redigeret af
        #394

        I går

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        • D Offline
          D Offline
          Doc4
          wrote on sidst redigeret af
          #395

          Her lidt om omkostninger for Dara kombier...RESULTS:
          The estimated cost per patient for each triplet regimen was $13,890 (DARA/BOR/DEX), $22,231 (IXA/LEN/DEX), $24,322 (ELO/LEN/DEX), $26,410 (DARA/LEN/DEX), and $27,432 (CAR/LEN/DEX). Drug acquisition costs and treatment duration were the largest drivers of cost. https://www.ncbi.nlm.nih.gov/pubmed/30917078

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          • D Offline
            D Offline
            Doc4
            wrote on sidst redigeret af
            #396

            Single-agent daratumumab in very advanced relapsed and refractory multiple myeloma patients: a real-life single-center retros.These real-life results revealed modest efficacy of single-agent daratumumab in advanced patients with RRMM in comparison with data from clinical trials. The overall response rate was 24%, including 5% very good partial response or better. After a median follow-up of 6.5 months, all patients experienced disease relapse. The median progression-free survival was 1.9 mo.

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            • D Offline
              D Offline
              Doc4
              wrote on sidst redigeret af
              #397

              https://www.ncbi.nlm.nih.gov/pubmed/30874850

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              • P Offline
                P Offline
                peter12
                wrote on sidst redigeret af
                #398

                "Most patients presented with high-risk characteristics", så det er vel ikke en normal gruppe ?

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                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #399

                  Lidt ringere end Sirius. 24% ORR vs 29% og median PFS 1,9 md vs. 3,7 md. Median antal forudgående behandlinger 4 vs 5. Om patienterne iøvrigt er sammenlignelige ved jeg ikke. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)01120-4/fulltext

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                  • B Offline
                    B Offline
                    bibob
                    wrote on sidst redigeret af
                    #400

                    Det er jo ikke kun Genmab. Markedet afventer nogle nøgletal i slut ugen. Faldet har ikke noget med hverken dårlige eller gode nyheder at gøre ift Genmab.

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #401

                      Vi må håbe at Car-t kommer ind her med noget bedre når dara/imid kombierne er udtømte.

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                      • Helge_LarsenPI-redaktørH Offline
                        Helge_LarsenPI-redaktørH Offline
                        Helge_LarsenPI-redaktør
                        wrote on sidst redigeret af
                        #402

                        Enig bibob . Alt ser rød ud her hos mig. 😞

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                        • Helge_LarsenPI-redaktørH Offline
                          Helge_LarsenPI-redaktørH Offline
                          Helge_LarsenPI-redaktør
                          wrote on sidst redigeret af
                          #403

                          Ham her er ikke ked af det. https://play.borsen.dk/social/5cac6c6e595ab4f00a3311e8

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                          • D Offline
                            D Offline
                            Doc4
                            wrote on sidst redigeret af
                            #404

                            T-cell acute lymphoblastic leukaemia (T-ALL) - “Dar”-ing to target CD38 in T-ALL. T-cell acute lymphoblastic leukemia = T-ALL. ..."This study is compelling because it provides strong evidence that daratumumab should have clinical efficacy in T-ALL"

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                            • D Offline
                              D Offline
                              Doc4
                              wrote on sidst redigeret af
                              #405

                              favicon

                              (www.bloodjournal.org)

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                              • T Offline
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                                transalp
                                wrote on sidst redigeret af
                                #406

                                Øhhe det lyder ret positivt 🙂 Doc4, den smule som lægmand forstår.. tak for link..

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                                • J Offline
                                  J Offline
                                  jkj
                                  wrote on sidst redigeret af
                                  #407

                                  Ifølge FDA,s tidsplan for RTOR, så bør godkendelse af Dara til 1 Linje komme i indeværende uge.

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                                  • B Offline
                                    B Offline
                                    bibob
                                    wrote on sidst redigeret af
                                    #408

                                    Fredag efter luk. 😉

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                                    • J Offline
                                      J Offline
                                      JKY_VH
                                      wrote on sidst redigeret af
                                      #409

                                      Det glæder vi os til;-)

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                                      • S Offline
                                        S Offline
                                        Schiff
                                        wrote on sidst redigeret af
                                        #410

                                        @pensionisten jeg synes faktisk ikke man kan sige at Genmab har klaret sig specielt godt YTD når man ser på resten
                                        af den eurofori der har været i C25.

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                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #411

                                          Genmab og c25 er begge steget ca 9% i år. Gen en bønne mindre. Januar var skrækkelig - betydeligt ringere end c25 - men siden er det gået fint.

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