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Genmab — Marts 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • T Offline
    T Offline
    transalp
    wrote on sidst redigeret af
    #981

    Go morgen.. 🙂

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    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #982

      Novatis Mayzent : https://www.reuters.com/article/us-fda-mayzent/novartis-gets-u-s-approval-for-new-drug-to-treat-multiple-sclerosis-idUSKCN1R8019

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      • BulderB Offline
        BulderB Offline
        Bulder
        wrote on sidst redigeret af
        #983

        https://www.novartis.com/news/media-releases/novartis-receives-fda-approval-mayzent-siponimod-first-oral-drug-treat-secondary-progressive-ms-active-disease

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        • B Offline
          B Offline
          bibob
          wrote on sidst redigeret af
          #984

          Også Celgene i MS. Der er kamp om det. https://m.firstwordpharma.com/hot-heels-eu-application-celgene-files-us-clearance-ozanimod-relapsing-multiple-sclerosis

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          • P Offline
            P Offline
            Parasitism
            wrote on sidst redigeret af
            #985

            God morgen 🙂

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #986

              from recent Conference, Tisotumab vedotin
              https://www.mdedge.com/hematology-oncology/article/197472/gynecologic-cancer/tisotumab-vedotin-shows-promise-recurrent

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              • P Offline
                P Offline
                polle1
                wrote on sidst redigeret af
                #987

                Godmorgen og god dag

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                • B Offline
                  B Offline
                  bibob
                  wrote on sidst redigeret af
                  #988

                  @pensionisten. Jeg håber at din kone må få nye og bedre behandlingsmuligheder. Der kommer heldigvis nye og forhåbentlig bedre medicin på markedet. Held og lykke. 🙂

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                  • J Offline
                    J Offline
                    JKY_VH
                    wrote on sidst redigeret af
                    #989

                    Også H&L herfra og god morgen:-)

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #990

                      8:28: det var så lidt. og held og lykke

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #991

                        and europe
                        https://www.globenewswire.com/news-release/2019/03/27/1773690/0/en/Genmab-Announces-European-Regulatory-Submission-for-Daratumumab-in-Combination-with-Bortezomib-Thalidomide-and-Dexamethasone-in-Frontline-Multiple-Myeloma.html?culture=fr-ca

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #992

                          they are on a roll!

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                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #993

                            Nu nærmer ASCO sig snart - ikke at det bliver den vigtigste konference for Genmab, men om ikke andet kommer der vel opdateringer på diverse dara-studier. Abstract deadlines:

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                            • S Offline
                              S Offline
                              Sukkeralf
                              wrote on sidst redigeret af
                              #994

                              ASCO Meetings

                              ASCO Meetings Program Guide

                              favicon

                              (meetings.asco.org)

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                              • S Offline
                                S Offline
                                Sukkeralf
                                wrote on sidst redigeret af
                                #995

                                Nice E L - did we get 100% sure on filing for sc dosing. Was the Columba data enough or.......?

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                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #996

                                  that's the million dollar question @Sukkeralf … well more like billion dollar question in this case lol

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                                  • S Offline
                                    S Offline
                                    Sukkeralf
                                    wrote on sidst redigeret af
                                    #997

                                    Bulders question: Can data from the Columba study be the basis for approval in all treatment lines in MM, or do we have to await the sc combo study MMY2040?

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                                    • B Offline
                                      B Offline
                                      bibob
                                      wrote on sidst redigeret af
                                      #998

                                      https://ir.genmab.com/news-releases/news-release-details/genmab-announces-european-regulatory-submission-daratumumab-3

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                                      • S Offline
                                        S Offline
                                        Sukkeralf
                                        wrote on sidst redigeret af
                                        #999

                                        jans answer: The COLUMBA study is the only non inferiority PHIII that would be needed to obtain a label for SC daratumumab...

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                                        • S Offline
                                          S Offline
                                          Sukkeralf
                                          wrote on sidst redigeret af
                                          #1000

                                          In order to obtain a broader label, we would also need to obtain safety data from the PLEIADES study which is evaluating 3 cohorts of patients DARA + RD, DARA + VMP and DARA + VRD. If this study reads out positively, we expect to obtain a broad label for SC DARA..

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