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Genmab — Marts 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #842

    GSK2857916 anti-BCMA in Nature https://www.nature.com/articles/s41408-019-0196-6

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #843

      meanwhile the it remains quiet around the JNJ anti-BCMA

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      • P Offline
        P Offline
        peter12
        wrote on sidst redigeret af
        #844

        It sounds a little toxic ? 😞

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #845

          it doesnt sound that bad, does it? they call it an "acceptable safety profile". We knew about blurred vision , Jan hinted at that before as a negative

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          • BulderB Offline
            BulderB Offline
            Bulder
            wrote on sidst redigeret af
            #846

            Nevertheless: "Corneal events led to dose reduction in 16 (46%) patients, and dose interruptions or delays in 17 (49%) patients."

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            • BulderB Offline
              BulderB Offline
              Bulder
              wrote on sidst redigeret af
              #847

              Manageable, yes, but they have to delay og reduce treatment.

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              • BulderB Offline
                BulderB Offline
                Bulder
                wrote on sidst redigeret af
                #848

                or

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                • StockBullS Offline
                  StockBullS Offline
                  StockBull
                  wrote on sidst redigeret af
                  #849

                  @bibob 14.36 hehehe du får det til at lyde som om AB er en storaktionær der kan styre genmabs kurs op eller ned efter behag. Faktum er at AB = markedet og markedet består af tusindvis af handlende men der kan selvfølgelig være noglre mega store aktøre blandt de tusindvis af handlende som kan påvirke kursen i en hvis grad.

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                  • B Offline
                    B Offline
                    bibob
                    wrote on sidst redigeret af
                    #850

                    Stockbull. Jeg er fuld ud klar over at AB ikke er een aktionær. Men mange store i den gruppe som AB repræsenterer har jo haft en interesse i at holde kursen nede. Det ville være rart om de kunne samarbejde om at få den til at stige som i dag.

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #851

                      But they are unsure why it seems that pts benefit better if no prior dara-treatment. Could be that pts are more ill. And notable: "Future studies may also investigate the use of GSK2857916 as a key component for combination with other therapies and in other MM populations."

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                      • T Offline
                        T Offline
                        transalp
                        wrote on sidst redigeret af
                        #852

                        Nejnej... det er ikk AB der er stor aktionær.. det er Aab - forever der er storaktionærer.. 😉

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #853

                          yes, yes, both is true. it will take a bit more time before we will hear something from the JNJ BCMA study, primary completion date is December 2019

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                          • StockBullS Offline
                            StockBullS Offline
                            StockBull
                            wrote on sidst redigeret af
                            #854

                            AB = markedet minus Danmark længere er den ikke 🙂

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                            • A Offline
                              A Offline
                              AaBforever
                              wrote on sidst redigeret af
                              #855

                              No..no.. jeg er kun en lille ydmyg aktionær..:-D

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                              • P Offline
                                P Offline
                                polle1
                                wrote on sidst redigeret af
                                #856

                                Tror lille frk. Maia meget snart checker ind på Hotel Genmab 🙂

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                                • StockBullS Offline
                                  StockBullS Offline
                                  StockBull
                                  wrote on sidst redigeret af
                                  #857

                                  Maria må godt snart komme i hus https://www.youtube.com/watch?v=jvYagLTa_GY

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                                  • G Offline
                                    G Offline
                                    gentogen
                                    wrote on sidst redigeret af
                                    #858

                                    Bemærk også. at de kun har inkluderet ECOG 0 og 1 (altså vedr. 15;36)

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #859

                                      @gentogen ; that should be seen as positive, right?

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                                      • P Offline
                                        P Offline
                                        peter12
                                        wrote on sidst redigeret af
                                        #860

                                        Only fit pts ? https://radiopaedia.org/articles/ecog-performance-status?lang=us

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #861

                                          yes

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                                          0

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