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Genmab — Februar 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #1180

    New trial (by Shaji Kumar) Daratumumab and Dexamethasone With Pomalidomide or Carfilzomib in Treating Patients With Relapsed Multiple Myeloma https://clinicaltrials.gov/ct2/show/NCT03841565?term=daratumumab+OR+ofatumumab+OR+tisotumab+OR+arzerra+OR+darzalex&lupd_s=02%2F15%2F2019&rank=1

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #1181

      Pollux completion date extended by half a year https://clinicaltrials.gov/ct2/history/NCT02076009?A=39&B=40&C=merged

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #1182

        I think they are giving MAIA participants on (Rd) arm who have sponsor-confirmed disease progression , the option to receive daratumumab https://clinicaltrials.gov/ct2/history/NCT02252172?A=47&B=48&C=merged

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #1183

          ethical decision?

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #1184

            ALL hospitals now recruiting in the HuMax-AXL-ADC trial (1 hospital removed) https://clinicaltrials.gov/ct2/history/NCT02988817?A=11&B=12&C=merged

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            • SolsenS Offline
              SolsenS Offline
              Solsen
              wrote on sidst redigeret af
              #1185

              Full speed 🙂

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              • BulderB Offline
                BulderB Offline
                Bulder
                wrote on sidst redigeret af
                #1186

                E L 17:41: That is the cross over problem we have discussed earlier. When they do that they

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                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #1187

                  will never get a reliable OS, as there is no control group to compare with.

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #1188

                    But maybe they have realized that Rd-pts would do it any way (cross over).

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #1189

                      maybe. i guess you can not stop them from taking Dara if they want to.

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #1190

                        ...just for the purpose of a 'clean' trial

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #1191

                          xactly, they can leave the study any time and pay for dara themselves. But now Janssen will pay for them. Nice move.

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                          • Helge_LarsenPI-redaktørH Offline
                            Helge_LarsenPI-redaktørH Offline
                            Helge_LarsenPI-redaktør
                            wrote on sidst redigeret af
                            #1192

                            Just a moment...

                            favicon

                            (www.proinvestor.com)

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                            • P Offline
                              P Offline
                              peter12
                              wrote on sidst redigeret af
                              #1193

                              Interessant artikel om atezo + dara https://www.medpagetoday.com/reading-room/asco/immunotherapy/78028

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                              • P Offline
                                P Offline
                                peter12
                                wrote on sidst redigeret af
                                #1194

                                Og det må være dette forsøg der er udvidet ? https://clinicaltrials.gov/ct2/show/NCT02431208?cond=NCT02431208&rank=1

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                                • Helge_LarsenPI-redaktørH Offline
                                  Helge_LarsenPI-redaktørH Offline
                                  Helge_LarsenPI-redaktør
                                  wrote on sidst redigeret af
                                  #1195

                                  God morgen. 🙂

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                                  • B Offline
                                    B Offline
                                    bibob
                                    wrote on sidst redigeret af
                                    #1196

                                    God morgen. :-). Skyfri himmel over Sæby. 🙂

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                                    • Helge_LarsenPI-redaktørH Offline
                                      Helge_LarsenPI-redaktørH Offline
                                      Helge_LarsenPI-redaktør
                                      wrote on sidst redigeret af
                                      #1197

                                      Ditto her i Regstrup. 🙂

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                                      • DarvinD Offline
                                        DarvinD Offline
                                        Darvin
                                        wrote on sidst redigeret af
                                        #1198

                                        Kan ikke huske om denne blev del den anden dag https://www.targetedonc.com/videos/key-takeaway-points-in-phase-iii-alcyone-trial-for-multiple-myeloma

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                                        • H Offline
                                          H Offline
                                          Hamming
                                          wrote on sidst redigeret af
                                          #1199

                                          Fedt svar fra Lassen https://twitter.com/Genmab/status/1093814035416522752

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