Genmab — November 2018

[Bulder]

Lyra har betydeligt ringere vgpr+ rate end Griffin. Tyder på at dara + Cybord bliver en parentes, bortset fra de lande, hvor der ikke råd til andet.

[Bulder]

De pusler stadig med at rette algoritmen i de robotter der sendte genmab ned sammen med Coloplast

[gentogen]

ADCT 301: In the 45 µg/kg dose group (dose escalation + expansion), the ORR was 80.8% (21/26 pts) and the CR rate was 50% (13/26 pts

[gentogen]

Conclusions: In pts with R/R cHL, therapy with Cami-T provided impressive ORRs and CR rates in a heavily pretreated pt population

[E_L]

sounds good!

[Bulder]

stærkt gentogen

[Parasitism]

https://www.nordnet.dk/mux/web/analys/nyheter/visaNyhet.html?itemid=326503009&sourcecode=hugin

[Bulder]

Nogen der har fundet noget amg420 eller bb2121?

[Parasitism]

Så kom det også på NN

[Thomas]

Wow ADCT 301 lyder super stærkt?

[henrik48]

Jeg må desværre have min onkolog-datter til at fortolke alle de informationer...lol

[henrik48]

Men det lyder altsammen lovende

[Bulder]

Ja i cHL. I NHL er responsraterne ikke så høje. https://ash.confex.com/ash/2018/webprogram/Paper115986.html

[Bulder]

henrik48: Spørg lige din datter om cHL er nemmere at behandle end NHL.

[Bulder]

Helge, er du på?

[henrik48]

@bulder - nu er hun neuroonkolog og ikke ekspert i blod...men jeg skal forsøge

[gentogen]

This is the first report of the use of daratumumab in LCDD. This antibody yielded rapid and significant hematologic responses in five of six heavily pretreated patients with this disease, preventing renal progression. Daratumumab represents a promising option for these patients and larger, international studies are warranted.

[Thomas]

A compound within a compound...

[Thomas]

Eller var det a pipeline within a compound. Either way...

[gentogen]

D-VMP provides a consistent and statistically significant PFS benefit relative to Rd continuous, Rd 18, and MPT