Genmab — Oktober 2018

[Solsen]

Min bemærkning var nok også for sjov. Men Elo bliver ikke til noget stort.

[Bulder]

Næppe. Men for patienterne er det fint med en mulighed mere. Dog nok ikke elo, når først dara sc er på banen. Elo's fordel nu er den korte infusionstid. En time efter de første 2 gange.

[Solsen]

Ja vi skal desværre vente et års tid eller mere på dara sc.

[E_L]

not enough advantage for elo even for Dara IV when physicians get accustomed to the 90 minute schedule

[Bulder]

I'm not sure how prevalent it is. Janssen has filed for approval of the split dosing of the first 2 infusions. But accelerated infusion has just the other day gone into phase 2. They can hardly finish that study before sc dara is there.

[Bulder]

Rubbish. Not the first 2. AFTER the first 2 ...

[jkj]

Darzalex vej til frontline i DK pris ca. 78 mill. dkr.https://www.regioner.dk/media/5210/dara-rev-dex-v103.pdf

[jkj]

De 78 mill var kun region hovedstaden og brutto kroner for ialt 4120 behandlinger med mindre jeg regner bruger en forkert endhedspris

[jkj]

Her er Holsterbro 2100 enheder og ca 36 mill. dkr.

[jkj]

https://docplayer.dk/70749036-Laegemidlets-navn-daratumumab-darzalex-i-kombination-med-bortezomib-dexamethason.html

[Bulder]

20:48 is also wrong. Split dosing is about 1. infusion only. The former accelerated dosing schedule was after 2 infusions. The new phase 2 study starts accelerated 90 min infusion after only 1 half first dose.

[mobbyduck1]

@JKJ hvor har du prisen fra??

[E_L]

@Bulder I was basing myself a bit on this article we saw earlier this year, "Adoption of the More Rapid Infusion Protocol

A number of myeloma treat­ment centers in the United States are either using the new 90-minute Darzalex infusion protocol, or planning to do so in the near future" https://myelomabeacon.org/news/2018/04/30/shorter-darzalex-infusion-times/

[E_L]

Kenneth Anderson | ESH MM 2018 | Future combinations for the treatment of MM - http://www.multiplemyelomahub.com/medical-information/kenneth-anderson-esh-mm-2018-future-combinations-for-the-treatment-of-mm

[E_L]

ESMO Abstracts @ midnight

[jkj]

mobbyduck prisen er offentligt kendt små. og kan findes på nettet små 19000 kr. pr 20 ml.

[mobbyduck1]

ja, men sygeshusapotekerne betaler langt mindre end de listepriser du anfører

[Raffles]

@EL 22:18, As far as I can see it it only some of the posters being released at midnight. Proffered Papers and Posters for discussion will only be released Oct 19th. In case GEN should be so lucky having some of these.......

[jkj]

yes lets hope that we dont find some from genmab now

[Raffles]

Maybe some for now and the rest later:-)