Genmab — Oktober 2018

NiklasZ

Selvom der er et godt stykke op til 1200 og langt op til 1600, så kan vi vel forvente et godt stormløb ind i aktien igen, hvis MAIA kommer med positivt resultat.

Bulder

Dara-pom-dex blev jo godkendt pba et fase 1 studie. Hørte engang Paul Richardson i en video sige at han brugte elo før dara i 3. linje. Hvis elo så ikke virkede kunne dara komme ind.

Solsen

Min bemærkning var nok også for sjov. Men Elo bliver ikke til noget stort.

Bulder

Næppe. Men for patienterne er det fint med en mulighed mere. Dog nok ikke elo, når først dara sc er på banen. Elo's fordel nu er den korte infusionstid. En time efter de første 2 gange.

Solsen

Ja vi skal desværre vente et års tid eller mere på dara sc.

E_L

not enough advantage for elo even for Dara IV when physicians get accustomed to the 90 minute schedule

Bulder

I'm not sure how prevalent it is. Janssen has filed for approval of the split dosing of the first 2 infusions. But accelerated infusion has just the other day gone into phase 2. They can hardly finish that study before sc dara is there.

Bulder

Rubbish. Not the first 2. AFTER the first 2 ...

jkj

Darzalex vej til frontline i DK pris ca. 78 mill. dkr.https://www.regioner.dk/media/5210/dara-rev-dex-v103.pdf

jkj

De 78 mill var kun region hovedstaden og brutto kroner for ialt 4120 behandlinger med mindre jeg regner bruger en forkert endhedspris

jkj

Her er Holsterbro 2100 enheder og ca 36 mill. dkr.

jkj

https://docplayer.dk/70749036-Laegemidlets-navn-daratumumab-darzalex-i-kombination-med-bortezomib-dexamethason.html

Bulder

20:48 is also wrong. Split dosing is about 1. infusion only. The former accelerated dosing schedule was after 2 infusions. The new phase 2 study starts accelerated 90 min infusion after only 1 half first dose.

mobbyduck1

@JKJ hvor har du prisen fra??

E_L

@Bulder I was basing myself a bit on this article we saw earlier this year, "Adoption of the More Rapid Infusion Protocol

A number of myeloma treatment centers in the United States are either using the new 90-minute Darzalex infusion protocol, or planning to do so in the near future" https://myelomabeacon.org/news/2018/04/30/shorter-darzalex-infusion-times/

E_L

Kenneth Anderson | ESH MM 2018 | Future combinations for the treatment of MM - http://www.multiplemyelomahub.com/medical-information/kenneth-anderson-esh-mm-2018-future-combinations-for-the-treatment-of-mm

E_L

ESMO Abstracts @ midnight

jkj

mobbyduck prisen er offentligt kendt små. og kan findes på nettet små 19000 kr. pr 20 ml.

mobbyduck1

ja, men sygeshusapotekerne betaler langt mindre end de listepriser du anfører

Raffles

@EL 22:18, As far as I can see it it only some of the posters being released at midnight. Proffered Papers and Posters for discussion will only be released Oct 19th. In case GEN should be so lucky having some of these.......