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Genmab — Oktober 2018

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • B Offline
    B Offline
    bikube
    wrote on sidst redigeret af
    #2020

    Lørdag præsenteres data fra Tiso fase 2a i livmoderhalskræft - siger Nordnets kalender.

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    • R Offline
      R Offline
      Raun
      wrote on sidst redigeret af
      #2021

      Vil næsten vædde på at AQR minsker deres short position i disse dage....

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #2022

        this one, https://ir.genmab.com/news-releases/news-release-details/genmab-and-seattle-genetics-announce-tisotumab-vedotin-data-be Bulder just gave you the link where it will be published -tomorrow already. Only poster presentation, so i expect nothing more in the weekend ?

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        • DarvinD Offline
          DarvinD Offline
          Darvin
          wrote on sidst redigeret af
          #2023

          Kkjoel m fl mht strategi. Har en fast position i Gen idet jeg tror fuldt ud på aktien. Har dog samtidig, hvert år og gentaget, spekulerer i Bull på den. Sammenlagt har det været en super investering. Har aldrig rørt Bear mht Genmab - tør ikke

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          • T Offline
            T Offline
            Thomas
            wrote on sidst redigeret af
            #2024

            Troede kun vi fik TV data på ESMO?

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            • JørgenVarnæsJ Offline
              JørgenVarnæsJ Offline
              JørgenVarnæs
              wrote on sidst redigeret af
              #2025

              ok - tak. så er der vist ingen grund til at sidde på stilke over wekenden

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #2026

                Huge New trial, D-RVd, 690 patients Ph III, SC,
                https://clinicaltrials.gov/ct2/show/NCT03710603?term=daratumumab+OR+ofatumumab+OR+tisotumab&lupd_s=10%2F18%2F2018&rank=3

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #2027

                  this was Griffin https://clinicaltrials.gov/ct2/show/NCT02874742?term=MMY2004&rank=2
                  and this one was announce in the summer https://clinicaltrials.gov/ct2/show/NCT03652064?term=Daratumumab+VELCADE+Lenalidomide+Dexamethasone&rank=2

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #2028

                    so the differnence with the summer trial is transplant or not? (summer was also already SC)

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #2029

                      this Ofatumumab RMS -autoinjector trial started recruiting https://clinicaltrials.gov/ct2/history/NCT03560739?A=1&B=2&C=merged

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                      • BulderB Offline
                        BulderB Offline
                        Bulder
                        wrote on sidst redigeret af
                        #2030

                        Yes, the new one must be the continuation of Griffin in the transplant setting.

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #2031

                          But primary outcome still pfs and nor mrd, which is secondary. Pfs up to 9(!) years.

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                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #2032

                            nor=not

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #2033

                              But it does not rule out a filing for approval after Griffin-read-out. An approval can be given on the condition of a phase 3 study.

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #2034

                                9 years??? wtf...
                                hadn't seen that yet...

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                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #2035

                                  good point. anyway , it points to a good read-out, doesn't it, otherwise you dont start 2 (big) trials so fast afterwards

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                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #2036

                                    Primary completion May 2029! I'm sure they'll file.

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #2037

                                      ... after the phase 2.

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #2038

                                        sounds very comforting

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #2039

                                          the JNJ BCMA CD3 DuoBody is near primary completion date on Nov 1; they moved the final completion date to Oct 2019 ; 1 year earlier https://clinicaltrials.gov/ct2/history/NCT03145181?A=10&B=11&C=merged

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