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Genmab — Oktober 2018

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • JørgenVarnæsJ Offline
    JørgenVarnæsJ Offline
    JørgenVarnæs
    wrote on sidst redigeret af
    #2019

    spændende om vi endelig hører mere fra klinikken her over weekenden. Blev vi ikke lovet både TF og AXL data her til ESMO?

    1 Reply Last reply
    0
    • B Offline
      B Offline
      bikube
      wrote on sidst redigeret af
      #2020

      Lørdag præsenteres data fra Tiso fase 2a i livmoderhalskræft - siger Nordnets kalender.

      1 Reply Last reply
      0
      • R Offline
        R Offline
        Raun
        wrote on sidst redigeret af
        #2021

        Vil næsten vædde på at AQR minsker deres short position i disse dage....

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #2022

          this one, https://ir.genmab.com/news-releases/news-release-details/genmab-and-seattle-genetics-announce-tisotumab-vedotin-data-be Bulder just gave you the link where it will be published -tomorrow already. Only poster presentation, so i expect nothing more in the weekend ?

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          • DarvinD Offline
            DarvinD Offline
            Darvin
            wrote on sidst redigeret af
            #2023

            Kkjoel m fl mht strategi. Har en fast position i Gen idet jeg tror fuldt ud på aktien. Har dog samtidig, hvert år og gentaget, spekulerer i Bull på den. Sammenlagt har det været en super investering. Har aldrig rørt Bear mht Genmab - tør ikke

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            • T Offline
              T Offline
              Thomas
              wrote on sidst redigeret af
              #2024

              Troede kun vi fik TV data på ESMO?

              1 Reply Last reply
              0
              • JørgenVarnæsJ Offline
                JørgenVarnæsJ Offline
                JørgenVarnæs
                wrote on sidst redigeret af
                #2025

                ok - tak. så er der vist ingen grund til at sidde på stilke over wekenden

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #2026

                  Huge New trial, D-RVd, 690 patients Ph III, SC,
                  https://clinicaltrials.gov/ct2/show/NCT03710603?term=daratumumab+OR+ofatumumab+OR+tisotumab&lupd_s=10%2F18%2F2018&rank=3

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #2027

                    this was Griffin https://clinicaltrials.gov/ct2/show/NCT02874742?term=MMY2004&rank=2
                    and this one was announce in the summer https://clinicaltrials.gov/ct2/show/NCT03652064?term=Daratumumab+VELCADE+Lenalidomide+Dexamethasone&rank=2

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #2028

                      so the differnence with the summer trial is transplant or not? (summer was also already SC)

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                      0
                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #2029

                        this Ofatumumab RMS -autoinjector trial started recruiting https://clinicaltrials.gov/ct2/history/NCT03560739?A=1&B=2&C=merged

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #2030

                          Yes, the new one must be the continuation of Griffin in the transplant setting.

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                          0
                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #2031

                            But primary outcome still pfs and nor mrd, which is secondary. Pfs up to 9(!) years.

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #2032

                              nor=not

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                              0
                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #2033

                                But it does not rule out a filing for approval after Griffin-read-out. An approval can be given on the condition of a phase 3 study.

                                1 Reply Last reply
                                0
                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #2034

                                  9 years??? wtf...
                                  hadn't seen that yet...

                                  1 Reply Last reply
                                  0
                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #2035

                                    good point. anyway , it points to a good read-out, doesn't it, otherwise you dont start 2 (big) trials so fast afterwards

                                    1 Reply Last reply
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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #2036

                                      Primary completion May 2029! I'm sure they'll file.

                                      1 Reply Last reply
                                      0
                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #2037

                                        ... after the phase 2.

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                                        0
                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #2038

                                          sounds very comforting

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                                          0

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