Genmab — September 2018
-
New Phase 2 trial: Daratumumab Plus Ibrutinib in Patients With Waldenstrӧm's Macroglobulinemia https://clinicaltrials.gov/ct2/show/NCT03679624?term=daratumumab+OR+ofatumumab+OR+tisotumab&lupd_s=09%2F20%2F2018&rank=1
-
Molecular Templates and Takeda to Take on Multiple Myeloma in Deal Worth up to $632 Million https://www.biospace.com/article/am6a-molecular-templates-and-takeda-to-take-on-multiple-myeloma-in-deal-worth-up-to-632-million/
-
The increasing knowledge of disease biology allowed to recognise new potential therapeutic targets, such as CD38 that is expressed on the surface of almost half of WM malignant cells.133 Daratumumab, a monoclonal antibody against CD38, approved for the treatment of multiple myeloma, is a promising agent for the treatment of WM
-
-
Livet er langt..lykken er kort...så lad os se om det holder.
-
production failure for Yescarta or Kymriah (in lymphoma)? https://twitter.com/DrMiguelPerales/status/1042592569664983042
-
auktionen ser altså underlig ud
-
Hi Jan,
Da data readout er hændelse (event)-driven (IDMC kigge på data så snart en forudbestemt antal af patienter har fået deres sygdom tilbage, kendt som pfs [progression free survial]), er det svært at sige hvornår data kommer. Vi monitere hastighed af disse 'events' og vi forventer at data kommer i de kommende tid, i 2018.
FYI, Vi har ikke set data så denne er spekulativ, men da der er robuste moderne data for Rev/dex i denne patient-befolkning, kan det faktum, at det forudbestemte antal
-
hændelser endnu ikke er nået, indikere, at PFS for dara arm er længere end oprindeligt planlagt. Som sagt, det er spekulativ, da vi ikke har set data. Også interessant at kigge på er at data fra Pollux studier viser at Dara Rev/dex-combo fungerer godt i anden linje (ASH 2017: 24 måneder PFS - median pfs ikke nået endnu), så vi glæder os til at se hvor godt det vil fungere i første linje (POLLUX-data fortsætter med at vise stærkere data, hver gang opdateringen gives).
Yours,
Rachel -
tak for det jkj
Hello! It looks like you're interested in this conversation, but you don't have an account yet.
Getting fed up of having to scroll through the same posts each visit? When you register for an account, you'll always come back to exactly where you were before, and choose to be notified of new replies (either via email, or push notification). You'll also be able to save bookmarks and upvote posts to show your appreciation to other community members.
With your input, this post could be even better 💗
Tilmeld Log ind