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Genmab — Juni 2018

Planlagt Fastgjort Låst Flyttet Genmab
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  • P Offline
    P Offline
    Plimsoller
    wrote on sidst redigeret af
    #599

    Second they are speaking about the CAR-T results presented at ASCO. As we know they hopefully/expected 15-18 months progression free, but the result was around 12.

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    • P Offline
      P Offline
      Plimsoller
      wrote on sidst redigeret af
      #600

      The expert said that CAR-T is not to be considered to be a competitor to Darzalex. This due to cost and treatment “mode”. 3-4 weeks in the hospital etc.

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #601

        tak 😉

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #602

          Subcutaneous daratumumab show benefit in patients with relapsed or refractory multiple myeloma https://www.youtube.com/watch?v=16TrK-zfVms

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          • P Offline
            P Offline
            Plimsoller
            wrote on sidst redigeret af
            #603

            Lastet they touches upon who the focus lies on during these types of conferences - JNJ or Genmab. It is clearly on JNJ, but this year Genmab was for the first time represented physically (a booth or something I imagine), and the interpretation is that they therefore have a lot of faith in their pipeline.

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            • StockBullS Offline
              StockBullS Offline
              StockBull
              wrote on sidst redigeret af
              #604

              Plimsoller. So to get this right. The patients died after 12 month or ?

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              • P Offline
                P Offline
                Plimsoller
                wrote on sidst redigeret af
                #605

                Lastet = lastly. Sorry - I am on the phone.

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                • P Offline
                  P Offline
                  Plimsoller
                  wrote on sidst redigeret af
                  #606

                  They said that Bluebird presented results which showet 12 months progression free, where the analysis were hoping for 15-18 months.

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                  • P Offline
                    P Offline
                    Plimsoller
                    wrote on sidst redigeret af
                    #607

                    Not sure about the exact definition of progression free. The expert emphadized that CAR-T is not a cure. This was the hope 6 months ago.

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                    • P Offline
                      P Offline
                      Plimsoller
                      wrote on sidst redigeret af
                      #608

                      You are welcome

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                      • StockBullS Offline
                        StockBullS Offline
                        StockBull
                        wrote on sidst redigeret af
                        #609

                        progression free survival ? PFS

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                        • P Offline
                          P Offline
                          Plimsoller
                          wrote on sidst redigeret af
                          #610

                          Sorry, but I don’t know.

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                          • P Offline
                            P Offline
                            Plimsoller
                            wrote on sidst redigeret af
                            #611

                            Børsen shows 1 video for free every day. Maybe someone with more knowledge than me can have a look:)

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                            • StockBullS Offline
                              StockBullS Offline
                              StockBull
                              wrote on sidst redigeret af
                              #612

                              As far as I know it means the time it take before the disease get worse or the patient die - but I am not 100% sure

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                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #613

                                Pfs er tiden, hvor sygdommen holdes i ro - altså ikke forværres - og hvor patienten stadig er i live.

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                                • H Offline
                                  H Offline
                                  hda
                                  wrote on sidst redigeret af
                                  #614

                                  ... og alle er glade 🙂 Bulder er tilbage på chatten! 🙂

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                                  • Legolas23L Offline
                                    Legolas23L Offline
                                    Legolas23
                                    wrote on sidst redigeret af
                                    #615

                                    @Gentogen Fik vi svar igår og afklaret i forhold til Dara i mono Vs solide? Ellers på interesserede ressourcepersoner gerne spole et døgn tilbage på Chatten til ca 16.44 og frem.

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                                    • G Offline
                                      G Offline
                                      gentogen
                                      wrote on sidst redigeret af
                                      #616

                                      Hvis du tænker på 15.44 så er det JNJ-63723283, der er mono plus i to kombier med hhv. Dara og Erdafitinib

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                                      • G Offline
                                        G Offline
                                        gentogen
                                        wrote on sidst redigeret af
                                        #617

                                        I Nivolumab Dara studiet (15.57) er der en Dara mono arm i e tunderstudie, men det er i MM

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                                        • G Offline
                                          G Offline
                                          gentogen
                                          wrote on sidst redigeret af
                                          #618

                                          Hvis jeg ellers selv kan holde styr på det efterhånden....

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