Genmab — Juni 2018
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This is the MMY-2036 mentioned in Genmabs announcement, and according to that it was "discontinued". So when the change of recruitment status was made as late as 21. of june, it could mean that they will not recruit any more, but let the current participants continue. But not sure.
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@E.L...I do not know about the extension both in time and patients enrolled, but the data from the study will be rather easy to comprahend by layman (press/analytics), because "..Pathologic response measured from the surgical specimen." - that means you will have the affected removed prostata in the lab. Better be good results;)
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I forbindelse med den pris Darzalex fik i Spanien i sidste uge, udtaler den lokale Janssen direktør at 52% har CR og 1 ud af 3 MRD i kombinationsbehandling. Det må være de tal fra Pollux ? http://www.gacetamedica.com/suplementos/premios-fundamed/el-jurado-reconoce-a-darzalex-por-su-innovacion-en-el-tratamiento-del-mieloma-multiple-YD1603313
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HuMax®-AXL-ADC Progress Triggers Milestone Payment to Seattle Genetics
Company Announcement Genmab to pay Seattle Genetics, Inc. a milestone payment of USD 7 million under the Antibody-Drug Conjugate (ADC)...
GlobeNewswire News Room (www.globenewswire.com)
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human AXL fremskridt, kan vel kun være gode tegn
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Det betyder i det mindste, at det har vist sig sikkert at bruge det og at de har fundet den/de relevante dosis. The dose escalation part has two dose escalation arms: the first arm investigates a once every 3 weeks (1Q3W) dosing schedule and the second arm investigates a three administrations over 4 weeks (3Q4W) dosing schedule.
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