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Genmab — Marts 2018

Planlagt Fastgjort Låst Flyttet Genmab
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  • P Offline
    P Offline
    pauly
    wrote on sidst redigeret af
    #496

    Darzalex highligtet

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    • P Offline
      P Offline
      pauly
      wrote on sidst redigeret af
      #497

      As for Darzalex, Duato stated that J&J has a "very ambitious development program" for the drug. He said that Darzalex already claims a market share of around 20% as a second-line treatment for multiple myeloma. The "next wave of growth" for the drug will be in the first-line setting, according to Duato. He said J&J considers the drug as a backbone therapy in multiple myeloma.

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      • StockBullS Offline
        StockBullS Offline
        StockBull
        wrote on sidst redigeret af
        #498

        🙂 Morning fra Thailand.

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        • StockBullS Offline
          StockBullS Offline
          StockBull
          wrote on sidst redigeret af
          #499

          Det her med Dara Rosen reducere fra 90 ml til 15 ml hvordan skal det forstaar. Vil det medfoere at Dara salget falder mon ?og er
          det mon derfor shorterne stadig er aktive

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          • StockBullS Offline
            StockBullS Offline
            StockBull
            wrote on sidst redigeret af
            #500

            Just a moment...

            favicon

            (journals.lww.com)

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            • Helge_LarsenPI-redaktørH Offline
              Helge_LarsenPI-redaktørH Offline
              Helge_LarsenPI-redaktør
              wrote on sidst redigeret af
              #501

              God morgen. 🙂

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              • P Offline
                P Offline
                Plimsoller
                wrote on sidst redigeret af
                #502

                God morgen 🙂

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                • B Offline
                  B Offline
                  bibob
                  wrote on sidst redigeret af
                  #503

                  God morgen 🙂

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                  • B Offline
                    B Offline
                    bibob
                    wrote on sidst redigeret af
                    #504

                    Når Dara bliver first Line vil der alt andet lige blive brugt mere. Læg mærke til den næst sidste linie i linket StockBull " that's a lot of Dara being used globaly "

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                    • P Offline
                      P Offline
                      polle1
                      wrote on sidst redigeret af
                      #505

                      God morgen 🙂

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                      • P Offline
                        P Offline
                        pauly
                        wrote on sidst redigeret af
                        #506

                        mornings 🙂

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                        • T Offline
                          T Offline
                          transalp
                          wrote on sidst redigeret af
                          #507

                          go morgen : )

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                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #508

                            StockBull: Der indgår stadig 1800 mg dara. Men blandingsvæsken med hyaluronidase er mere koncentreret nu (15 ml) end før, hvor blandingen skulle mixes manuelt og kom helt op på 90 ml i blandt. Så stor mængde blandingsvæske skulle indgives med en sprøjtepumpe og tog længere tid.

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #509

                              i would think you can safely assume that 1 dose of Dara SC will cost (at least) the same as 1 dose of Dara IV, irrespective of how much ml is in that dose

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                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #510

                                Yes because the amount of dara is the same.

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                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #511

                                  For lige at præcisere: Mængden af dara er den samme (1800 mg) uanset om man blander manuelt med hyaluronidase på klinikken og får op til 90 ml, eller om man modtager det pre-mixed fra fabrikken i 15 ml færdige doser.

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                                  • R Offline
                                    R Offline
                                    Raffles
                                    wrote on sidst redigeret af
                                    #512

                                    På AACR har BMS et Abstract #2603 (….colorectal cancer treated with Nivolumab + Ipilimumab in checkmate -142, 16. april). De øvrige drugs (DARA og Cobimetinib) står dog ikke nævnt i overskriften!
                                    Endvidere har de Abstract #1727 (antitumor actitity associated with dual targeting of CD38 and PD-1 pathways in preclinical models, 16. april).
                                    Mon der kommer noget brugbart nyt d. 16. april??

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #513

                                      i wast just reading this one " Furthermore, TTI-622 potentiates the efficacy of daratumumab and cetuximab in hematological and solid xenograft tumor models, respectively" http://www.abstractsonline.com/pp8/#!/4562/presentation/9327

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #514

                                        that is the way to clarify it Bulder, thanks

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                                        • M Offline
                                          M Offline
                                          mobbyduck1
                                          wrote on sidst redigeret af
                                          #515

                                          Bergenbio er også med på AACH:

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