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Genmab — Januar 2018

Planlagt Fastgjort Låst Flyttet Genmab
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  • S Offline
    S Offline
    Sukkeralf
    wrote on sidst redigeret af
    #2150

    Er det tid til en fredagsnyhed

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    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #2151

      Alene i DK er der 4700 personer/år der udvikler brystkræft. Og hvis 20% af disse overudtrykker HER2 med dårlig prognose, så er behovet stort på verdensplan.

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #2152

        Is it pure coïncidence that this company (in Utrecht, just next to Genmab) announces first dosing of bispecific antibody targeting HER2 and HER3 receptors today?? Merus Announces First Patient Dosed in a Phase 2 Clinical Trial of MCLA-128 in Two Metastatic Breast Cancer Patient Populations
        https://www.pharmiweb.com/pressreleases/pressrel.asp?ROW_ID=262078

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        • S Offline
          S Offline
          Sukkeralf
          wrote on sidst redigeret af
          #2153

          Det er bare et hårdt prøvet target

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #2154

            A Study to Evaluate Subcutaneous Daratumumab in Combination With Standard Multiple Myeloma Treatment Regimens https://clinicaltrials.gov/ct2/show/NCT03412565?term=daratumumab+OR+ofatumumab&lupd_s=01%2F25%2F2018&rank=4

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #2155

              this could become a very important study, backbone Dara, choose what combo you want, D-VRd , D-VMP or D-Rd.

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #2156

                completion date sept 19, very fast?

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                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #2157

                  Phase 2. Will they file?

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                  • A Offline
                    A Offline
                    AaBforever
                    wrote on sidst redigeret af
                    #2158

                    Det går squ´meget godt nu 🙂

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                    • A Offline
                      A Offline
                      AaBforever
                      wrote on sidst redigeret af
                      #2159

                      Som sagt før " Genmab er som en rutschebane i Fårup...det går SÅ hurtigt ned og OP 🙂

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #2160

                        good point. thinking out-loud; we already have the SubQ vs IV study which is Phase 3; maybe this is the Ph2 we need in the middle to get that one approved?

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #2161

                          we had a similar situation before, no?

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #2162

                            I mean, the IV combo's should be approved by then?

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #2163

                              sorry, not should be , WILL be 😉

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                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #2164

                                Do you ask Winkel if this means that these 2 studies can be the basis for an overall approval of sc in all lines and settings?

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                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #2165

                                  ok - good idea

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                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #2166

                                    If so, it means that sc can be launched in 2020. - Just like Novod predicts.

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                                    • Helge_LarsenPI-redaktørH Offline
                                      Helge_LarsenPI-redaktørH Offline
                                      Helge_LarsenPI-redaktør
                                      wrote on sidst redigeret af
                                      #2167

                                      Vi kan vist stadig være enig om at shorterne i aktien er meget venlige og humane. Vi ser absolut ingen aggressivitet og forsøg på at trykke kursen ned under støttepunkter og udløse stop loses over en bred kam.

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                                      • Helge_LarsenPI-redaktørH Offline
                                        Helge_LarsenPI-redaktørH Offline
                                        Helge_LarsenPI-redaktør
                                        wrote on sidst redigeret af
                                        #2168

                                        Enig med Pensionisten. Der er udmattelse at spore. Det har vi dog prøvet før gennem årene.

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                                        • Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktør
                                          wrote on sidst redigeret af
                                          #2169

                                          Jeg formoder, at vi kursmæssigt danner base for øjeblikket. Nyorienteringen starter så efter næste Q&A d. 22. februar. 🙂

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