Genmab — Januar 2018
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GEN patent på HER2 ADC! Hvor passer den ind pre clinical? http://www.freshpatents.com/-dt20180125ptan20180022816.php
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Men senere står der: ...high capacity for killing cancer cells expressing high or low levels of HER2 when administered as an antibody drug conjugate (ADC), no substantial agonistic effect on the proliferation of HER2-expressing cancer cells, and provide for effective ADCC-mediated killing of HER2-expressing cells, as well as any combination of the foregoing properties.
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Is it pure coïncidence that this company (in Utrecht, just next to Genmab) announces first dosing of bispecific antibody targeting HER2 and HER3 receptors today?? Merus Announces First Patient Dosed in a Phase 2 Clinical Trial of MCLA-128 in Two Metastatic Breast Cancer Patient Populations
https://www.pharmiweb.com/pressreleases/pressrel.asp?ROW_ID=262078 -
A Study to Evaluate Subcutaneous Daratumumab in Combination With Standard Multiple Myeloma Treatment Regimens https://clinicaltrials.gov/ct2/show/NCT03412565?term=daratumumab+OR+ofatumumab&lupd_s=01%2F25%2F2018&rank=4
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Det går squ´meget godt nu
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Som sagt før " Genmab er som en rutschebane i Fårup...det går SÅ hurtigt ned og OP
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