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Genmab — Januar 2018

Planlagt Fastgjort Låst Flyttet Genmab
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  • nohopeN Offline
    nohopeN Offline
    nohope
    wrote on sidst redigeret af
    #2130

    Probably just hoping for a paycheck - every month. I know the feeling.

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    0
    • Helge_LarsenPI-redaktørH Offline
      Helge_LarsenPI-redaktørH Offline
      Helge_LarsenPI-redaktør
      wrote on sidst redigeret af
      #2131

      God morgen. 🙂

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      0
      • B Offline
        B Offline
        bibob
        wrote on sidst redigeret af
        #2132

        God morgen.

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        • P Offline
          P Offline
          Parasitism
          wrote on sidst redigeret af
          #2133

          god morgen 🙂

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          • D Offline
            D Offline
            DevOp
            wrote on sidst redigeret af
            #2134

            God morgen, itf kombi med PD1/PD-L1 tror jeg først, at vi ser statistiske resultater, der viser en evt forskel - altså ikke historier om enkelte pts forløb. Det må være dybde af respons, OR og ikke mindst længde af respons, der ser ud til at blive forbedret, når Dara for alvor kommer i spil ved opregulering af CD38 - hvor PD1 inhibitors ellers normalt ser ud til at miste virkningen.

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            • M Offline
              M Offline
              Mcjean
              wrote on sidst redigeret af
              #2135

              Go'morgen der falder en bombe i US i dag se link i aktiesnakken, korruption på højeste niveau i administrationen i US, hele det socialistiske, globalistiske korthus vælter i aften med Hillary, Obama og FBI i spidsen. Overvældende beviser og masser af informanter i FBI.

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              • T Offline
                T Offline
                transalp
                wrote on sidst redigeret af
                #2136

                go morgen 🙂

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                0
                • S Offline
                  S Offline
                  Sukkeralf
                  wrote on sidst redigeret af
                  #2137

                  ClinicalTrials.gov

                  favicon

                  (clinicaltrials.gov)

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                  • S Offline
                    S Offline
                    Sukkeralf
                    wrote on sidst redigeret af
                    #2138

                    Humax IL8 er ikke helt død endnu 🙂

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #2139

                      oh that is a nice find! I was just looking at genmab website yesterday, i think they just updated/ maintained a bit http://www.genmab.com/product-pipeline/products-in-development

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                      • J Offline
                        J Offline
                        JKY_VH
                        wrote on sidst redigeret af
                        #2140

                        Kan kun læse overskriften https://medwatch.dk/secure/Medicinal___Biotek/article10243049.ece?utm_source=Feed&utm_medium=latest

                        1 Reply Last reply
                        0
                        • P Offline
                          P Offline
                          pauly
                          wrote on sidst redigeret af
                          #2141

                          Ya it looks good

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                          0
                          • P Offline
                            P Offline
                            Parasitism
                            wrote on sidst redigeret af
                            #2142

                            Det er ikke meget der sker i chatten i dag. Did you drink too many heineken last night E L?

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                            • bongobobB Offline
                              bongobobB Offline
                              bongobob
                              wrote on sidst redigeret af
                              #2143

                              GEN patent på HER2 ADC! Hvor passer den ind pre clinical? http://www.freshpatents.com/-dt20180125ptan20180022816.php

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                              • S Offline
                                S Offline
                                Sukkeralf
                                wrote on sidst redigeret af
                                #2144

                                de har også taget på HER2 CD3

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                                • G Offline
                                  G Offline
                                  gentogen
                                  wrote on sidst redigeret af
                                  #2145

                                  Jeg mener ikke, at det er er ADC. Citat: "It is an object of the present invention to provide novel highly specific and effective monoclonal HER2 antibodies for medical use"

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                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #2146

                                    it is not an easy text to read... they try to keep as many options open as they can within the patent description i guess. very interesting though.

                                    1 Reply Last reply
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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #2147

                                      no Para, i am fine lol, just 1.

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #2148

                                        Men senere står der: ...high capacity for killing cancer cells expressing high or low levels of HER2 when administered as an antibody drug conjugate (ADC), no substantial agonistic effect on the proliferation of HER2-expressing cancer cells, and provide for effective ADCC-mediated killing of HER2-expressing cells, as well as any combination of the foregoing properties.

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                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #2149

                                          Så det er sikkert ligesom Tiso. Kan noget ADCC på egen hånd, men virker bedst konjugeret med et giftstof.

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                                          0

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