Genmab — December 2017
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Sidste udtalelse fra Novod om c-t: .We continue to believe that the CAR-T data looks good, but also that the competition in earlier lines of MM will likely be quite limited and that CAR-T initially will also be restrained by the high cost (up to USD 1-1.5m per patient), which at least will keep the main use for the highly refractory patient population with very limited treatment options. Hence, we also still expect a significant rebound in a stock like Genmab when the CAR-T hype settles a bit
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haha - prøv at få den igennem NICE's evalueringsmodel...
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https://en.m.wikipedia.org/wiki/Dendreon Similarities
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http://files.shareholder.com/downloads/AMDA-KPIBN/3691997971x0x966333/8815E418-E24F-48D8-9137-B552120120C5/Chari_MMY1001_D-KRd.pdf 91% VGPR or better in first line. But MRD at same level as ALCYONE.
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Det er svært at se car-t der
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Mono smoldering er ikke daras styrke i mono http://files.shareholder.com/downloads/AMDA-KPIBN/3691997971x0x966352/72AB296C-DF10-4895-BFF3-302682BB24FC/Hofmeister_SMM2001_10Dec17_0947.pdf
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Ja, men det var først efter ASCT. Før ASCT var MRDneg 38% https://ash.confex.com/ash/2017/webprogram/Paper102714.html
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https://clinicaltrials.gov/ct2/show/NCT03224507?cond=NCT03224507&rank=1 Ja tror at man i dette forsøg prøver at lægge dara oven på.
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http://brianduriemd.myeloma.org/?q=us-cure-trial Her omtales disse "cure" forsøg.
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er det ikke bygget ind i alle de store first line forsøg?
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