Genmab — November 2017

[E_L]

could be spam

[jkj]

ORR 90,9

[sowise]

?

[E_L]

reuters https://www.reuters.com/article/health-johnsonjohnson-myeloma/jj-multiple-myeloma-drug-succeeds-in-first-line-combination-study-idUSL1N1NQ1TK

[JKY_VH]

Tak E L , bibob og jkj

[GeorgeBest]

Thanks E L

[jkj]

ikke late breaker såvidt jeg kan se ,
præsenteres på næste ash møde om 1 måned ifølge reuters

[jkj]

eller hva ?

[gentogen]

Tak for link. Ser solidt ud.

[gentogen]

The rate of complete responses, meaning no detectable cancer in the blood or bone marrow, was 42.6 percent for Darzalex versus 24.4 percent for the standard regimen.

[rex_pacis]

thanks @e

[sowise]

en kurs
belønning kom der ikke ud af det

[Bulder]

Det er lavere CR end Pollux i 2. linje

[OHW]

Data er ikke interessante nok til at løfte kursen..

[JKY_VH]

"Dr. Kenneth Anderson, the ASH president, called the responses “impressive,” but added they were likely to be viewed as even more significant outside the United States.
The trial was primarily conducted in Europe using the standard first-line regimen there. Celgene Corp’s Revlimid is part of the standard regimen used in the United States.
“It likely will be the basis for approval of daratumumab to be incorporated into the initial combination therapy of myeloma,” Anderson said of the results."

[OHW]

..behandlingen er ikke så relevant i US, hvor det store marked er her og nu..

[kbsv]

De her 1. linie patienter kommer til at være på Dara længe! Her tror jeg der lurer en positiv trigger. Hvad kalkuleres der mon med nu, blandt analytikerne?

[Plimsoller]

Er der ikke blevet publiceret nogle late breaking abstracts endnu?

[Bulder]

kan være de så slet ikke søger godkendelse i us men afventer maia?

[pcf]

LBA-4
Phase 3 Randomized Study of Daratumumab Plus Bortezomib, Melphalan, and Prednisone (D-VMP) Versus Bortezomib, Melphalan, and Prednisone (VMP) in Newly Diagnosed Multiple Myeloma (NDMM) Patients (Pts) Ineligible for Transplant (ALCYONE)