Genmab — Oktober 2017
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Jeg ved JKY. Men hvor tit skal patienten have Revlimid? Hvor tit skal han have dex?
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Det vil jo nok vise sig med Cassiopeia, som er for transplantationsegnede, hvor vedligeholdelse kommer ind i billedet. I studiet er vedligeholdelse beskrevet som 16 mg (dvs 1 infusion) hver ottende uge i 2 år. https://www.clinicaltrials.gov/ct2/show/NCT02541383?term=cassiopeia&rank=1
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I MMY2004 D-RVd, er dara vedligehold ligeledes hver 8. uge. Revlimid vedligehold er oftere https://www.clinicaltrials.gov/ct2/show/NCT02874742?term=mmy2004&rank=1
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10 mg koster dkk 2614 og 15 mg dkk 2751 if
lg. mdecincinpriser.dk -
Halozymes today announced that Janssen has initiated the first of three planned Phase 3 clinical trials evaluatin a subcutaneous (SC) delivery of Darzalex with Halozymes proprietary ENHANZE technology.
The initial Phase 3 study is in amyloidosis with additional Phase 3 studies in multiple myeloma and smoldering myeloma patients planned for near-term initiation. -
Med nuværende problemer, som er vanskelige at se en løsning på vil CAR-T aldrig have en chance i firstline, når alternativet er en sikker behandling. Tænk på hvor enkelt en sc-dara og rev pille vil være first line. I denne behandling og måske også med Velcade vil en pæn del af patienterne også blive helbredt.
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