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Genmab — Oktober 2017

Planlagt Fastgjort Låst Flyttet Genmab
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  • S Offline
    S Offline
    Sukkeralf
    wrote on sidst redigeret af
    #2228

    Novartis confirms leadership in multiple sclerosis (MS) with scientific advancements and new data presented at ECTRIMS

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    • S Offline
      S Offline
      Sukkeralf
      wrote on sidst redigeret af
      #2229

      54 accepterede abstracts - godt at vi har en engageret partner for ofatumumab, når vi får data i 2019

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      • S Offline
        S Offline
        Sukkeralf
        wrote on sidst redigeret af
        #2230

        Novartis management suggested that siponimod could act as a "bridge" between its marketed oral MS therapy Gilenya and ofatumumab, an anti-CD20 monoclonal antibody that is in two Phase III studies for relapsing MS.

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        • S Offline
          S Offline
          Sukkeralf
          wrote on sidst redigeret af
          #2231

          Ofatumumab – marketed already as the chronic lymphocytic leukaemia treatment Arzerra – could emerge as a key competitor to Ocrevus, which is enjoying a strong launch in the US market. Furthermore, Novartis believes its product could benefit from a number of advantages; ofatumumab is a fully-human monoclonal antibody (Ocrevus is humanised), it can be administered via subcutaneous injection (instead of intravenously) and

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          • S Offline
            S Offline
            Sukkeralf
            wrote on sidst redigeret af
            #2232

            based on cross-trial comparisons, it has demonstrated faster B-cell repletion. These factors could determine that ofatumumab is a more patient and physician-friendly treatment, argues Novartis; a view shared by KOLs recently interviewed by FirstWord for our forthcoming report. Phase III studies should complete in 2019.

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            • DarvinD Offline
              DarvinD Offline
              Darvin
              wrote on sidst redigeret af
              #2233

              Dejlige linier og link Sukker - tak for det

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              • Helge_LarsenPI-redaktørH Offline
                Helge_LarsenPI-redaktørH Offline
                Helge_LarsenPI-redaktør
                wrote on sidst redigeret af
                #2234

                God morgen:-)

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                • SolsenS Offline
                  SolsenS Offline
                  Solsen
                  wrote on sidst redigeret af
                  #2235

                  Har du et link

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                  • N Offline
                    N Offline
                    NextLifeDK
                    wrote on sidst redigeret af
                    #2236

                    6:43

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                    • StockBullS Offline
                      StockBullS Offline
                      StockBull
                      wrote on sidst redigeret af
                      #2237

                      @Sukkeralf: Hvor stort mon the potentielle marked er for Ofatumumab og hvornår begynder der mon at komme pæne betalinger til Genmab

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                      • G Offline
                        G Offline
                        gentogen
                        wrote on sidst redigeret af
                        #2238

                        A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-54767414 (Daratumumab) in Healthy Participants

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                        • G Offline
                          G Offline
                          gentogen
                          wrote on sidst redigeret af
                          #2239

                          ClinicalTrials.gov

                          favicon

                          (clinicaltrials.gov)

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                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #2240

                            Stock bull er spået til at blive multi BB - tror det var 3-4 millarder dollars i omsætning. Så lad os håbe at Novartis kan få et BB stof ud af ofatumumab, hvis data er gode. En godkendelse kan være i hus i 2020 og royalty for de autoimmune sygdomme ligger vist på 15% eller husker jeg forkert ?

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                            • S Offline
                              S Offline
                              Sukkeralf
                              wrote on sidst redigeret af
                              #2241

                              StockBull Ocrevus er spået til at blive en multi BB............

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                              • J Offline
                                J Offline
                                jkj
                                wrote on sidst redigeret af
                                #2242

                                Fatter ikke hvad det forsøg går ud på gentogen, kan du eller anden forklare ?

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                                • S Offline
                                  S Offline
                                  Sukkeralf
                                  wrote on sidst redigeret af
                                  #2243

                                  Næh man synes det burde været lavet for lang tid siden

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                                  • S Offline
                                    S Offline
                                    Sukkeralf
                                    wrote on sidst redigeret af
                                    #2244

                                    Og hvis det var noget man virkelig gerne ville vide, så kunne det vel udføres ekstremt hurtigt, så det virker måske mere som nogle data der blot skal være klar ved indsendelse af registeringsansøgning

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #2245

                                      it looks like a safety study to test the safety of subcutaneous dosing on healthy participants ?

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #2246

                                        On Teprotumumab I add the link to the genmab site
                                        (i doubt many will know it has anything to do with Genmab...) http://www.genmab.com/product-pipeline/products-in-development/teprotumumab#tab1

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                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #2247

                                          jkj: der er for at undersøge hvad dara gør ved kroppen og hvordan kroppen reagerer på dara sammenlignet med raske mennesker, som ikke får dara. Og så er det for at undersøge om præmedicinering med steroider gør nogen forskel.

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