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Genmab — Oktober 2017

Planlagt Fastgjort Låst Flyttet Genmab
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  • B Offline
    B Offline
    bibob
    wrote on sidst redigeret af
    #2226

    Tak for link Sukker. - Godt at se at Teprotumumab komme i gang med PH III.

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    • J Offline
      J Offline
      JKY_VH
      wrote on sidst redigeret af
      #2227

      Tak Sukkeralf og god morgen

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      • S Offline
        S Offline
        Sukkeralf
        wrote on sidst redigeret af
        #2228

        Novartis confirms leadership in multiple sclerosis (MS) with scientific advancements and new data presented at ECTRIMS

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        • S Offline
          S Offline
          Sukkeralf
          wrote on sidst redigeret af
          #2229

          54 accepterede abstracts - godt at vi har en engageret partner for ofatumumab, når vi får data i 2019

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          • S Offline
            S Offline
            Sukkeralf
            wrote on sidst redigeret af
            #2230

            Novartis management suggested that siponimod could act as a "bridge" between its marketed oral MS therapy Gilenya and ofatumumab, an anti-CD20 monoclonal antibody that is in two Phase III studies for relapsing MS.

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            • S Offline
              S Offline
              Sukkeralf
              wrote on sidst redigeret af
              #2231

              Ofatumumab – marketed already as the chronic lymphocytic leukaemia treatment Arzerra – could emerge as a key competitor to Ocrevus, which is enjoying a strong launch in the US market. Furthermore, Novartis believes its product could benefit from a number of advantages; ofatumumab is a fully-human monoclonal antibody (Ocrevus is humanised), it can be administered via subcutaneous injection (instead of intravenously) and

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              • S Offline
                S Offline
                Sukkeralf
                wrote on sidst redigeret af
                #2232

                based on cross-trial comparisons, it has demonstrated faster B-cell repletion. These factors could determine that ofatumumab is a more patient and physician-friendly treatment, argues Novartis; a view shared by KOLs recently interviewed by FirstWord for our forthcoming report. Phase III studies should complete in 2019.

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                • DarvinD Offline
                  DarvinD Offline
                  Darvin
                  wrote on sidst redigeret af
                  #2233

                  Dejlige linier og link Sukker - tak for det

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                  • Helge_LarsenPI-redaktørH Offline
                    Helge_LarsenPI-redaktørH Offline
                    Helge_LarsenPI-redaktør
                    wrote on sidst redigeret af
                    #2234

                    God morgen:-)

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                    • SolsenS Offline
                      SolsenS Offline
                      Solsen
                      wrote on sidst redigeret af
                      #2235

                      Har du et link

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                      • N Offline
                        N Offline
                        NextLifeDK
                        wrote on sidst redigeret af
                        #2236

                        6:43

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                        • StockBullS Offline
                          StockBullS Offline
                          StockBull
                          wrote on sidst redigeret af
                          #2237

                          @Sukkeralf: Hvor stort mon the potentielle marked er for Ofatumumab og hvornår begynder der mon at komme pæne betalinger til Genmab

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                          • G Offline
                            G Offline
                            gentogen
                            wrote on sidst redigeret af
                            #2238

                            A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-54767414 (Daratumumab) in Healthy Participants

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                            • G Offline
                              G Offline
                              gentogen
                              wrote on sidst redigeret af
                              #2239

                              ClinicalTrials.gov

                              favicon

                              (clinicaltrials.gov)

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                              • S Offline
                                S Offline
                                Sukkeralf
                                wrote on sidst redigeret af
                                #2240

                                Stock bull er spået til at blive multi BB - tror det var 3-4 millarder dollars i omsætning. Så lad os håbe at Novartis kan få et BB stof ud af ofatumumab, hvis data er gode. En godkendelse kan være i hus i 2020 og royalty for de autoimmune sygdomme ligger vist på 15% eller husker jeg forkert ?

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                                • S Offline
                                  S Offline
                                  Sukkeralf
                                  wrote on sidst redigeret af
                                  #2241

                                  StockBull Ocrevus er spået til at blive en multi BB............

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                                  0
                                  • J Offline
                                    J Offline
                                    jkj
                                    wrote on sidst redigeret af
                                    #2242

                                    Fatter ikke hvad det forsøg går ud på gentogen, kan du eller anden forklare ?

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                                    • S Offline
                                      S Offline
                                      Sukkeralf
                                      wrote on sidst redigeret af
                                      #2243

                                      Næh man synes det burde været lavet for lang tid siden

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                                      • S Offline
                                        S Offline
                                        Sukkeralf
                                        wrote on sidst redigeret af
                                        #2244

                                        Og hvis det var noget man virkelig gerne ville vide, så kunne det vel udføres ekstremt hurtigt, så det virker måske mere som nogle data der blot skal være klar ved indsendelse af registeringsansøgning

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #2245

                                          it looks like a safety study to test the safety of subcutaneous dosing on healthy participants ?

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                                          0

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