Genmab — Juni 2017

[E_L]

but lets forget about Dara anyway now, it is all about solid tumours from now on #optimist

[E_L]

what are your first thoughts on those results? it doesnt really say what sort of response the patients had
...

[Mcjean]

Since they want to present it on an upcoming medical konference, it can be that bad:-)

[Solsen]

As I recall the pts was some kind late stage. So its hard to say its not good. Cervical had very good preclinical results. I think we have to wait and se.

[Mcjean]

And if they finish recruting same time we can expect the other studies soon maybe?

[Solsen]

7 pts still ongoing is good.

[Mcjean]

This one was big with 34 of 173 in seven different types, so maybe the other one are even better maybe but pure speculation.

[Solsen]

I expectet the best results in cervical and ovary cancer....

[Sukkeralf]

I protokollen står der stage Ib or less, så umiddelbart ikke så syge - det undrer mig dog lidt

[Sukkeralf]

Det er nok en god ide at kigge lidt grundigt på dette, for man kan nok let overse et eller andet.

[Solsen]

https://www.cancer.gov/about-cancer/treatment/drugs/cervical#2

[Solsen]

Godt set sukker. Har vi mon ikke en poster fra de allerførste data mon.

[Helge_LarsenPI-redaktør]

Siden findes ikke

(borsen.dk)

[Solsen]

http://www.medscape.com/viewarticle/842038#vp_1 Lidt om Avastin.

[Solsen]

Mon ikke man overvejer et evt kombiforsøg...

[Solsen]

..og hvorfor ikke dara

[Solsen]

http://files.shareholder.com/downloads/AMDA-KPIBN/3968132968x0x832683/D1560CA8-68E1-49D1-ACB5-D5072F83B6E5/2015_ASCO_TF-ADC_GEN701_Lassen_poster_FINAL.pdf "Advanced cancer" i fase 1 forsøget

[Solsen]

Inclusion Criteria:

• Patients with relapsed, advanced and/or metastatic cancer who have failed available standard treatments or who are not candidates for standard therapy.

[Solsen]

De er vel rimeligt udsatte patienter...

[Sukkeralf]

Ja og de cervical patienter der er har stage 4 - når man læse om behandling af stage 1a og 1b ligner det absolut heller ikke patienter man ville give tisotumab. Der er vist lidt opklaringsarbejde der venter