Genmab — Juni 2017

[Solsen]

As I recall the pts was some kind late stage. So its hard to say its not good. Cervical had very good preclinical results. I think we have to wait and se.

[Mcjean]

And if they finish recruting same time we can expect the other studies soon maybe?

[Solsen]

7 pts still ongoing is good.

[Mcjean]

This one was big with 34 of 173 in seven different types, so maybe the other one are even better maybe but pure speculation.

[Solsen]

I expectet the best results in cervical and ovary cancer....

[Sukkeralf]

I protokollen står der stage Ib or less, så umiddelbart ikke så syge - det undrer mig dog lidt

[Sukkeralf]

Det er nok en god ide at kigge lidt grundigt på dette, for man kan nok let overse et eller andet.

[Solsen]

Drugs Approved for Cervical Cancer

This page lists cancer drugs approved by the Food and Drug Administration (FDA) for cervical cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

(www.cancer.gov)

[Solsen]

Godt set sukker. Har vi mon ikke en poster fra de allerførste data mon.

[Helge_LarsenPI-redaktør]

Siden findes ikke

(borsen.dk)

[Solsen]

http://www.medscape.com/viewarticle/842038#vp_1 Lidt om Avastin.

[Solsen]

Mon ikke man overvejer et evt kombiforsøg...

[Solsen]

..og hvorfor ikke dara

[Solsen]

http://files.shareholder.com/downloads/AMDA-KPIBN/3968132968x0x832683/D1560CA8-68E1-49D1-ACB5-D5072F83B6E5/2015_ASCO_TF-ADC_GEN701_Lassen_poster_FINAL.pdf "Advanced cancer" i fase 1 forsøget

[Solsen]

Inclusion Criteria:

• Patients with relapsed, advanced and/or metastatic cancer who have failed available standard treatments or who are not candidates for standard therapy.

[Solsen]

De er vel rimeligt udsatte patienter...

[Sukkeralf]

Ja og de cervical patienter der er har stage 4 - når man læse om behandling af stage 1a og 1b ligner det absolut heller ikke patienter man ville give tisotumab. Der er vist lidt opklaringsarbejde der venter

[Sukkeralf]

Stage 4 og 2b var det

[kkjoel]

Sukkeralf, på ClinicalTrials.gov kan jeg, ved de to "tisotumab"-studier, kun finde at "exclusion criteria - Cervical carcinoma of Stage 1B or less." Hvor finder du
protokollerne henne?

[Sukkeralf]

Dem er nu bare dem jeg mener