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Genmab — April 2017

Planlagt Fastgjort Låst Flyttet Genmab
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  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #1539

    Haven't heard anything about the 2nd NICE Committee meeting on Apr 20, thought those meetings were public. Looks like we have to wait until July for the small chance they will surprise us with a UK approval. https://www.nice.org.uk/guidance/indevelopment/gid-ta10076

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    • B Offline
      B Offline
      bibob
      wrote on sidst redigeret af
      #1540

      Er der nogen der har adgang og kan se om Dara blev godkendt af EMA. ? http://medwatch.dk/secure/Medicinal___Biotek/article9526585.ece?utm_campaign=Middag&utm_content=2017-04-24 12%3A16%3A13&utm_medium=top&utm_source=Feed

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #1541

        We are waiting for the European Comission now, who should approve based on the positive recommendation EMA already gave -if i am correc
        t?

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        • B Offline
          B Offline
          bibob
          wrote on sidst redigeret af
          #1542

          Yes that`s right. It should come this week . I guess Friday.

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          • B Offline
            B Offline
            bibob
            wrote on sidst redigeret af
            #1543

            LUK : 1310. 😉

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            • BulderB Offline
              BulderB Offline
              Bulder
              wrote on sidst redigeret af
              #1544

              @ gentogen: dit link ang dara pom i går kl 10:51 skulle vist have været dette her 😉 https://www.youtube.com/watch?v=-6M0a51-xyw

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              • BulderB Offline
                BulderB Offline
                Bulder
                wrote on sidst redigeret af
                #1545

                Men rigtigt, han er meget begejstret for dara-pom

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                • J Offline
                  J Offline
                  JKY_VH
                  wrote on sidst redigeret af
                  #1546

                  er du ikke lidt beskeden bibob?

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                  • B Offline
                    B Offline
                    bibob
                    wrote on sidst redigeret af
                    #1547

                    Jo.- Det var da et elendigt bud. 😄

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                    • J Offline
                      J Offline
                      JKY_VH
                      wrote on sidst redigeret af
                      #1548

                      ja, nu må du stramme dig an:-)

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                      • B Offline
                        B Offline
                        bibob
                        wrote on sidst redigeret af
                        #1549

                        Skal nok. 😞

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                        • G Offline
                          G Offline
                          gentogen
                          wrote on sidst redigeret af
                          #1550

                          Tak Bulder! Helt rigtigt.

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                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #1551

                            Og Sagar Lonial er jo ikke hvem som helst. Han har et hav af ledende tillidsposter inden for MM. FDA kan umuligt gå uden om godkendelse af dara-pom 🙂

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                            • G Offline
                              G Offline
                              gentogen
                              wrote on sidst redigeret af
                              #1552

                              Lidt apropos: http://www.myelomabeacon.com/docs/ash2016/492.pdf

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                              • G Offline
                                G Offline
                                gentogen
                                wrote on sidst redigeret af
                                #1553

                                Se konklusionerne!

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                                • T Offline
                                  T Offline
                                  Thomas
                                  wrote on sidst redigeret af
                                  #1554

                                  "From our data 80% of these heavily pretreated patients that were penta- refractory were alive at the 8 month follow up."

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                                  • T Offline
                                    T Offline
                                    Thomas
                                    wrote on sidst redigeret af
                                    #1555

                                    "These extended survival results are surprising and suggest the benefits of DARA and POM last beyond progression clear biological rationale should be investigated."

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                                    • T Offline
                                      T Offline
                                      Thomas
                                      wrote on sidst redigeret af
                                      #1556

                                      Det lyder hyggeligt nok 🙂

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #1557

                                        Det mest overraskende er at de kan fremvise en ORR på 33,3% i cohort 3, hvor pts er resistente over for både dara og pom. Men kombinerer man dem, så sker der ting og sager.

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                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #1558

                                          Her er det abstract, som svarer til de slides, som gentogen linkede til kl. 17:46 http://www.bloodjournal.org/content/128/22/492

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