Genmab — April 2017
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Fandt lige dette gamle udsag: “We presented sensational data from tisotumab vedotin at ASCO last year, but no one really noticed them because Darzalex took all the attention. The market has a tendency to only focus on one thing at a time,” says Jan van de Winkel.
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Genmab accelerates research efforts
Genmab will need to identify its next winning ticket in the coming three to four years, and its CEO is fully convinced that the drug is already hiding in the biotech company’s pipeline. The firm is now increasing its R&D budget in a bid to identify the winner.
(medwatch.dk)
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@Helge (og andre), læste den forholdsvis komplekse forklaring på PD-1/PD-L1 virkningsmekanismen, og kunne se det beskrevet ift forsøg, at det forventes også at kunne ramme metastaser i hjernen. Som jeg forstår det ift PD-1, sker påvirkningen i nærmiljøet omkring kræftcellerne ved at hæmme PD-1. Det må betyde, at PD-1 hæmmere skal passere BBB (Blood-Brain-Barrier) for at påvirke metastaser i hjernen. Det ser ud til, at T-lymfocytter godt kan passere BBB, men jeg mangler lidt viden om Daras
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DevOp..Jeg opfatter det som om at den immunmodulerende virkning er generel i kroppen og lymfocytterne kan som du skriver passere BBB. Det er dog kun et gæt fra min side. Tjekker op på det senere i dag, hvis jeg får tiden til det.
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Novartis-chef: Det trækker op til medicinboom i Kina
En række nye initiativer fra myndighederne i Kina betyder, at det trækker op til et kæmpe opsving i salget af medicin i Kina. Det mener Novartis’ adm. direktør Joe Jimenez.
(medwatch.dk)
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Her er et lille trick til dem der læser videnskabelige artikler. Det gør det nemt at downloade full text hvis det: http://www.sciencealert.com/this-new-browser-plugin-lets-you-access-millions-of-scientific-papers-for-free
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Ny stilling i Genmab. Der bliver virkelig oprustet. http://uniqueconsult.dk/head-of-global-drug-safety/
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hmm - approval måske først i næste uge?
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