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Genmab — April 2017

Planlagt Fastgjort Låst Flyttet Genmab
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  • J Offline
    J Offline
    JKY_VH
    wrote on sidst redigeret af
    #1103

    Det er muligt du har ret Helge, men en joker er spørgsmålet om, hvor længe patienterne bliver i behandling med Darzalex. Vedligeholdelsesbehandlingen kan således godt overstige analytikernes estimater betydeligt.

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    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #1104

      Visse analytikere har et topsalgsestimat på 8 mia $ i MM alene. Hvis vi antager at det holder, så er 2.+ linje ca 4 mia værd. Og det er hvad dagens kurs ca afspejler. 2. linje ww er med andre ord fuldt indregnet. Det kan da godt være at EMA-godkendelse vil give lidt stigning, men næppe meget. Det helt helt afgørende er gode Alcyone-data, som vil sparke døren ind til 1. linje og dermed til den anden halvdel af markedet.

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      • G Offline
        G Offline
        GlobalMacro 0
        wrote on sidst redigeret af
        #1105

        Dear Genmab believers, I often see comments about “Dara MM sales fully priced in”. If you have 5 minutes, read these comments and I will promise you you’ll have a great Easter Sunday!

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        • G Offline
          G Offline
          GlobalMacro 0
          wrote on sidst redigeret af
          #1106

          Based on multiple drivers I believe Dara in MM is not fully priced in. And this has everything to do with the analyst projections, these just don’t reflect the data.

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          • G Offline
            G Offline
            GlobalMacro 0
            wrote on sidst redigeret af
            #1107

            What drives this?: 1) Analysts don’t have the courage to reflect the real data in their models (with a price target of +50% or even +100% they would look like fools to their customers, nobody has the courage to do this) 2) The penetration assumptions in first and second line are still very low

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            • G Offline
              G Offline
              GlobalMacro 0
              wrote on sidst redigeret af
              #1108
              1. Also the treatment duration per patient is very low. Analysts are accounting for 24 months Dara treatment, while we already saw in the Pollux data that the PFS is going +50 months, regarding first line we’ve already heard some doctors speaking of Dara maintenance in the range of 5 years till 10 years.
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              • G Offline
                G Offline
                GlobalMacro 0
                wrote on sidst redigeret af
                #1109

                SO, LET THIS ALL SINK IN FOR A MOMENT….

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                • G Offline
                  G Offline
                  GlobalMacro 0
                  wrote on sidst redigeret af
                  #1110

                  Average analyst model: low penetration in first line (20% - 50%) and 24 months Dara treatment, what if this gets updated to 60% - 75% first line penetration and 7,5 years of Dara treatment??! Conclusion: The current MM peak sales estimation is far from what it will be in 10 – 15 years from now. I believe the MM only sales will go to 15 – 20 billion.

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                  • G Offline
                    G Offline
                    GlobalMacro 0
                    wrote on sidst redigeret af
                    #1111

                    So what does this say, and how can you find out? There’s only one way and that is by making the calculations yourself.

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                    • G Offline
                      G Offline
                      GlobalMacro 0
                      wrote on sidst redigeret af
                      #1112

                      I did some calculations, based on the 15 and 20 billion peak sales scenario’s. And I put in a few very soft assumptions: 1) Total shares outstanding in 2030: 65 million (currently 61 million) 2) Net profit margin Genmab in 2030: 75% (With such high royalty income the margin in reality will be significant higher) 3) Average royalty: 18% 4) Currency USD/DKK: 7.00 DKK per 1 USD

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                      • G Offline
                        G Offline
                        GlobalMacro 0
                        wrote on sidst redigeret af
                        #1113

                        Based on these assumptions and a stock price of 2500 DKK the P/E will be: 15 billion USD peak sales = +/- 19 billion DKK royalty, 75% net profit = 14.2 billion DKK net profit = 11 P/E 15 billion USD peak sales = +/- 25 billion DKK royalty, 75% net profit = 18.9 billion DKK net profit = 8 P/E J&J at the moment has a P/E of 18 and Roche of 22, off course P/E’s at the moment are quite high however

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                        • G Offline
                          G Offline
                          GlobalMacro 0
                          wrote on sidst redigeret af
                          #1114

                          this would mean that with a stock price 4000 DKK and the assumptions above Genmab would still be under the P/E of J&J.

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                          • G Offline
                            G Offline
                            GlobalMacro 0
                            wrote on sidst redigeret af
                            #1115

                            LET THAT SINK IN: 4000 DKK would mean: 15 billion USD peak sales = 17 P/E 20 billion USD peak sales = 13 P/E

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                            • G Offline
                              G Offline
                              GlobalMacro 0
                              wrote on sidst redigeret af
                              #1116

                              Thus, when the penetration data and the duration of treatment per patient will reflect the reality, the peak sales will go up significantly, maybe even double from the current level. Therefore the stock price has room to move up to 4000 DKK based on MM alone.

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                              • G Offline
                                G Offline
                                GlobalMacro 0
                                wrote on sidst redigeret af
                                #1117

                                The real question is, do analyst have the courage to reflect the real data in their models? I believe this will happen, however will go very gradually: stock moves higher > analysts update their models. Of course this will not fully happen in the next 2 years, however when we keep getting good data (Pollux PFS updates, ORR in Alcyone study and faster than expected sales growth) the analysts will definitely have to update their models fast.

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                                • G Offline
                                  G Offline
                                  GlobalMacro 0
                                  wrote on sidst redigeret af
                                  #1118

                                  Would love to hear what you guys think, maybe I missed something. However, I believe the direction I’m going is sound. The assumptions of the analyst are very very low and with the data we’ve already seen the peak sales is going to beg significantly higher. Next time I’ll write a blog post 🙂

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                                  • Legolas23L Offline
                                    Legolas23L Offline
                                    Legolas23
                                    wrote on sidst redigeret af
                                    #1119

                                    Thank you for sharing your thougts

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                                    • T Offline
                                      T Offline
                                      Thomas
                                      wrote on sidst redigeret af
                                      #1120

                                      Great read, GM. Thx

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                                      • StockBullS Offline
                                        StockBullS Offline
                                        StockBull
                                        wrote on sidst redigeret af
                                        #1121

                                        4000kr per share in 2030 is not a lot. It's less than 10% per year the coming 13 years.

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                                        • StockBullS Offline
                                          StockBullS Offline
                                          StockBull
                                          wrote on sidst redigeret af
                                          #1122

                                          Not that 10% per year is not good. But there is a lot of shares on the marked that potentially could increase more than 10% annually.

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