Genmab — November 2015
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det er flot
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the anti-CD20 antibody ofatumumab represents a highly active and well tolerated treatment option in relapsed NLPHL. 3 months after the end of treatment, response was documented in 27/28 patients (96%; 95%-CI: 84%-100%). After a median follow-up of 26 months, 1-year and 2-year progression-free survival (PFS) estimates were 93% and 80%
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Jeg tænker lidt sådan her. Viagra kom først på markedet, men der blev hurtigt fulgt af lignende midler som Cialis, hvor mekanismen er den samme men stoffet et andet. Kan man ikke forestilles sig det samme kan ske med Dara - at man finder mekanismen og laver et andet stof - der kan konkurrere med Dara - straks ?
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Uden at gøre mig klog på medicinudvikling tror ikke det er så nemt nohope, specielt med kræftmidler. Der er vel en grund til at de store blockbustere som f.eks. Avastin kan sidde på markedet så længe uden ''bare'' at blive erstattet af en copycat.
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Er rimelig sikker på at patentet på Dara er meget omfattende, specielt da det jo netop er så niche ved at være bindende til et specifikt molekyle i kroppen
, CD38. -
http://www.google.com/patents/EP2580243A1?cl=en - The present
invention relates to antibodies directed to human CD38 and to uses of such antibodies, in particular therapeutic uses. -
Interim analysis på CASTOR studiet https://clinicaltrials.gov/ct2/show/NCT02076009?term=Daratumumab+lenalidomide&rank=2
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http://finance.yahoo.com/news/agenus-acquire-antibody-manufacturing-capability-210000160.html Jeg er så glad fordi jeg er igen er blevet medejer af et antibody manufactory plant
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Solsen - er der nyheder omkring interim analysen på castor?
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