Genmab — Januar 2015
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2:05 DuoBody
Platform: A Versatile Platform for Lead Discovery in the Final FormatAran F. Labrijn, Ph.D., Senior Scientist, Antibody Sciences, Genmab BV
The DuoBody
platform represents a novel and elegant post-production technology for the generation of stable bispecific antibodies. General strategies, and considerations, for bispecific antibody discovery will be discussed. The suitability of the DuoBody platform for bispecific discovery approaches, showing the importance to do this in the -
PEGS i Boston: Clinical Perspective of ADC Development
Michael K. Bauer, Ph.D., Senior Vice President, Clinical Development, Genmab
•Mechanism of action of HuMax-Tissue Factor-ADC
•Translation of preclinical research into the clinic
•Striking the right balance between patient safety and charting unknown clinical territory
•Beyond dose-escalation
•Patient selection - why, when and how
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