Genmab — December 2014
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Although median overall survival was not reached in either group in this interim analysis, there was a trend toward longer overall survival in the group who received carfilzomib (73.3% vs 65%; HR = 0.79; P=.018). However, the results did not cross the prespecified statistical boundary set by the statisticians when the trial s
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http://finance.yahoo.com/news/amgen-onyx-announce-detailed-results-160000281.html Et link alle kan komme på. Se specielt safety 7-8% døde under eller lige efter behandling.
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Siger hun til sidst at 100% af patienterne med Pomalyst respondere på behandling. Altså100% ORR ?
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Nej det hun siger er vidst at frontline patienterne i studiet responderer 100% og 50% af patienterne med pomalyst (R/R patienter)
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Her er en lille Amgen video http://investors.amgen.com/phoenix.zhtml?c=61656&p=irol-newsArticle&ID=1995470
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In the KRd and Rd groups, 14 percent versus 4.3 percent of patients achieved a stringent complete response, a measurement indicating superior depth of response... dette syntes jeg da ikke er fantastisk. Dog svært vide hvad de karakteriserer som stringent CR
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In a phase Ib study among patients with newly diagnosed, relapsed or refractory multiple myeloma (MM) the combination of daratumumab with standard treatments was well tolerated and resulted in high rates of response. Results on efficacy and safety of the ongoing trial were presented at the ASH Annual Meeting in San Francisco.
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