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Aktiesnakken — Marts 2010

Planlagt Fastgjort Låst Flyttet Aktiesnakken
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • J Offline
    J Offline
    jelle
    wrote on sidst redigeret af
    #1960

    vedr. EGFr

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    • D Offline
      D Offline
      deleted-user
      wrote on sidst redigeret af
      #1961

      jeg kan ikke huske det by heart, men i min hjerne er datoen januar eller juni 2009?

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      • J Offline
        J Offline
        jelle
        wrote on sidst redigeret af
        #1962

        ja juni ringer nemlig en klokke. Sidder og leger lidt og tænker over sponsors/investigators 90 dages deadline til at præsentere data

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        • D Offline
          D Offline
          deleted-user
          wrote on sidst redigeret af
          #1963

          At an interim survival analysis in January 2009, the study did not fulfill a criterion for early stopping after half the trial was completed

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          • D Offline
            D Offline
            deleted-user
            wrote on sidst redigeret af
            #1964

            An Independent Data Monitoring Committee (IDMC) has evaluated the interim results and concluded that the benefit-risk profile of zalutumumab

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            • D Offline
              D Offline
              deleted-user
              wrote on sidst redigeret af
              #1965

              he IDMC recommended that the trial should continue to enroll up to 273 patients and a final analysis performed. The final analysis will take

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              • D Offline
                D Offline
                deleted-user
                wrote on sidst redigeret af
                #1966

                take place once 231 deaths have occurred.

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                • J Offline
                  J Offline
                  jelle
                  wrote on sidst redigeret af
                  #1967

                  ja præcis, så fuld enrollment i juni

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                  • D Offline
                    D Offline
                    deleted-user
                    wrote on sidst redigeret af
                    #1968

                    Jun 10, 2009
                    Recruitment Completed in Zalutumumab Head and Neck Cancer Pivotal Study

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                    • J Offline
                      J Offline
                      jelle
                      wrote on sidst redigeret af
                      #1969

                      forsøger med en worst case analyse med udgangspunkt i de sidst optagne ptt fra jan til juni, hvori de 90 dage til dataanalyse er anvendt.

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                      • D Offline
                        D Offline
                        deleted-user
                        wrote on sidst redigeret af
                        #1970

                        du poster i debatten ikke?

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                        0
                        • J Offline
                          J Offline
                          jelle
                          wrote on sidst redigeret af
                          #1971

                          skal forsøge. Ved vi hvilken performance status (PS) ptt er i? i fase I/II studiet havde de en median PS på 1, dvs. relativt god almen

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                          0
                          • J Offline
                            J Offline
                            jelle
                            wrote on sidst redigeret af
                            #1972

                            tilstand

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                            • J Offline
                              J Offline
                              jelle
                              wrote on sidst redigeret af
                              #1973

                              her tænker jeg i relation til hvor længe ptt i BSC-armen kan forventes at overleve

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                              • D Offline
                                D Offline
                                deleted-user
                                wrote on sidst redigeret af
                                #1974

                                jeg tror vi blev i tvivl om hvor syge de var....men jeg ville tage worst case, det vil sige at de er i god fatning

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                                • J Offline
                                  J Offline
                                  jelle
                                  wrote on sidst redigeret af
                                  #1975

                                  jeg kan næsten ikke tro at de er i bedre almen tilstand end i fase I/II forsøget

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                                  • D Offline
                                    D Offline
                                    deleted-user
                                    wrote on sidst redigeret af
                                    #1976

                                    worst case er worst case 🙂 Jeg går ud fra at benchmark iøvrigt er Erbitux?

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                                    • SolsenS Offline
                                      SolsenS Offline
                                      Solsen
                                      wrote on sidst redigeret af
                                      #1977

                                      Det der er key issue er om Zalu forbedrer median survivel med mindst 50% i forhold til BSC armen

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                                      • J Offline
                                        J Offline
                                        jelle
                                        wrote on sidst redigeret af
                                        #1978

                                        undersøger lige nærmere

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                                        • SolsenS Offline
                                          SolsenS Offline
                                          Solsen
                                          wrote on sidst redigeret af
                                          #1979

                                          Men prøv at lave et debatindlæg

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                                          0

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