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Aktiesnakken — Marts 2010

Planlagt Fastgjort Låst Flyttet Aktiesnakken
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  • J Offline
    J Offline
    jelle
    wrote on sidst redigeret af
    #1959

    hej, har I dato for hvornår gen havde alle 273 pt i hus?

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    • J Offline
      J Offline
      jelle
      wrote on sidst redigeret af
      #1960

      vedr. EGFr

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      • D Offline
        D Offline
        deleted-user
        wrote on sidst redigeret af
        #1961

        jeg kan ikke huske det by heart, men i min hjerne er datoen januar eller juni 2009?

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        • J Offline
          J Offline
          jelle
          wrote on sidst redigeret af
          #1962

          ja juni ringer nemlig en klokke. Sidder og leger lidt og tænker over sponsors/investigators 90 dages deadline til at præsentere data

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          0
          • D Offline
            D Offline
            deleted-user
            wrote on sidst redigeret af
            #1963

            At an interim survival analysis in January 2009, the study did not fulfill a criterion for early stopping after half the trial was completed

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            • D Offline
              D Offline
              deleted-user
              wrote on sidst redigeret af
              #1964

              An Independent Data Monitoring Committee (IDMC) has evaluated the interim results and concluded that the benefit-risk profile of zalutumumab

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              0
              • D Offline
                D Offline
                deleted-user
                wrote on sidst redigeret af
                #1965

                he IDMC recommended that the trial should continue to enroll up to 273 patients and a final analysis performed. The final analysis will take

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                0
                • D Offline
                  D Offline
                  deleted-user
                  wrote on sidst redigeret af
                  #1966

                  take place once 231 deaths have occurred.

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                  • J Offline
                    J Offline
                    jelle
                    wrote on sidst redigeret af
                    #1967

                    ja præcis, så fuld enrollment i juni

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                    0
                    • D Offline
                      D Offline
                      deleted-user
                      wrote on sidst redigeret af
                      #1968

                      Jun 10, 2009
                      Recruitment Completed in Zalutumumab Head and Neck Cancer Pivotal Study

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                      • J Offline
                        J Offline
                        jelle
                        wrote on sidst redigeret af
                        #1969

                        forsøger med en worst case analyse med udgangspunkt i de sidst optagne ptt fra jan til juni, hvori de 90 dage til dataanalyse er anvendt.

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                        0
                        • D Offline
                          D Offline
                          deleted-user
                          wrote on sidst redigeret af
                          #1970

                          du poster i debatten ikke?

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                          0
                          • J Offline
                            J Offline
                            jelle
                            wrote on sidst redigeret af
                            #1971

                            skal forsøge. Ved vi hvilken performance status (PS) ptt er i? i fase I/II studiet havde de en median PS på 1, dvs. relativt god almen

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                            0
                            • J Offline
                              J Offline
                              jelle
                              wrote on sidst redigeret af
                              #1972

                              tilstand

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                              • J Offline
                                J Offline
                                jelle
                                wrote on sidst redigeret af
                                #1973

                                her tænker jeg i relation til hvor længe ptt i BSC-armen kan forventes at overleve

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                                • D Offline
                                  D Offline
                                  deleted-user
                                  wrote on sidst redigeret af
                                  #1974

                                  jeg tror vi blev i tvivl om hvor syge de var....men jeg ville tage worst case, det vil sige at de er i god fatning

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                                  • J Offline
                                    J Offline
                                    jelle
                                    wrote on sidst redigeret af
                                    #1975

                                    jeg kan næsten ikke tro at de er i bedre almen tilstand end i fase I/II forsøget

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                                    0
                                    • D Offline
                                      D Offline
                                      deleted-user
                                      wrote on sidst redigeret af
                                      #1976

                                      worst case er worst case 🙂 Jeg går ud fra at benchmark iøvrigt er Erbitux?

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                                      • SolsenS Offline
                                        SolsenS Offline
                                        Solsen
                                        wrote on sidst redigeret af
                                        #1977

                                        Det der er key issue er om Zalu forbedrer median survivel med mindst 50% i forhold til BSC armen

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                                        • J Offline
                                          J Offline
                                          jelle
                                          wrote on sidst redigeret af
                                          #1978

                                          undersøger lige nærmere

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                                          0

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