Genmab: Vigtige begivenheder på ASH 2020
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05/12-20 kl. 21:45 CET180Teclistamab (CD3xBCMA)J&J DuoBody præsentation, RRMS
05/12-20 kl. 23:00 CET290Talquetamab (CD3xGPRC5D)J&J DuoBody præsentation, RRMS
06/12-20 kl. 09:30 CET402Epcoritamab (CD3xCD20)Dosiseskaleringsdata (flere 48 mg patienter og med længere behandlingsvarighed)
06/12-20 kl. 15:00 CET1969HexaBody CD38Prækliniske data i MM, AML, DLBCL06/12-20 kl. 16:00 CET2276Daratumumab (CD38)J&J: MAIA opdatede data
06/12-20 kl. 21:00 CET412Daratumumab (CD38)J&J: APOLLO subkutane fase III-data, i RRMS (D-Pd vs Pd)
07/12-20 kl. 15:00 CET2790Epcoritamab (CD3xCD20)Semimekanistisk model for udvælgelse af RP2D dosis (48 mg)
07/12-20 kl. 16:00 CET549Daratumumab (CD38)J&J: GRIFFIN opdateret data efter 12 måneders vedligeholdelsesterapi i NDMM
07/12-20 kl. 17:00 CET552Daratumumab (CD38)J&J: ANDROMEDA AmyloidosisKilde: American Society of Hematology
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Iflg. nyhedsbrev fra STAT (Adam Feuerstein) skulle der på ASH-2020 været præsenteret nogle ret lovende resultater overfor medfødte blodsygdomme med den genediteringsteknik, der hedder Crisp/case-9 (årets Nobelprisvindere).
Preliminary but 'nothing short of great.' New data on CRISPR treatment for blood diseases suggest cure is possible
A CRISPR-based gene-editing therapy has shown shown sustained effectiveness in 10 patients with sickle cell disease or beta-thalassemia.
STAT (www.statnews.com)
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Nyhedsbrevet, der bl.a. direkte vedr. et afsnit om JNJ Darzalex, se
https://mailchi.mp/statnews/stat-plus-zika-vaccines-a-pharma-shakeup-the-evidence-gap-604750?e=311aef2bfc -
Siden ASH-2020 er kurserne på næsten alle CRISP/case-9 selskaber eksploderet. Dagens Zack artikel giver den heller ikke for lidt

CRISPR Gene Editing: Owning the Future of Medicine
In the Century of Biology, it pays to own the future of curing disease at the root.
Yahoo Finance (finance.yahoo.com)
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