Bavarian Nordic — August 2021
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Bavarian: Topchef fortrøstningsfuld om finansiering https://www.proinvestor.com/investornyt/687978/bavarian-topchef-fortrostningsfuld-om-finansiering
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Ali Salanti (Adaptvac) skriver på Linkedin:
Great news on our SARS-COV-2 vaccine presented as a novel virus like particle formulation. First human trial data show that the vaccine is very well tolerated. The clinical site reports that “In contrast to licensed SARS-CoV-2 vaccines, ABNCoV2’s safety profile is comparable to licensed protein-based vaccine such as hepatitis B vaccines and well tolerated even at doses beyond those that induce maximal immune-responses”. -
But most importantly the vaccine induces very high antibody responses (up to 12 fold compared to convalescent sera). Responses that are several fold higher than best in class mRNA vaccines ????. The potency of the vaccine platform is highlighted by the fact that even in the absence of adjuvants do we get high tittered responses, and even at the low vaccine doses.
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We originally believed the precise positioning of the ACE2 binding part of the SARS-COV-2 receptor binding domain on the rigid surface of the virus like particle should results in a focused anti-RBD response with superior virus neutralization efficacy, and indeed our data generated together with Århus University show that we effectively neutralize the delta variant but more importantly we also very effectively (and importantly, better than
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convalescence sera and mRNA vaccine induced sera) neutralize the escape variants represented in our study including the Beta variant. This vaccine(candidate) is also characterized by being rock stable even at ambient temperatures for longer time periods, and combining this with superior antibody responses we hope such a vaccine can not only be deployed in this part of the world as a booster vaccine, but also in parts of the world where the cold chain cannot be assured. Sadly, only 1% of people
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Dansk vaccine har lang vej til godkendelse trods stærke data
https://www.proinvestor.com/investornyt/688439/dansk-vaccine-har-lang-vej-til-godkendelse-trods-staerke-data -
Zea - det vil blive modtaget med stor taknemlighed hvis nødpennen viser gode omsætningstakter. Vi kan håber lidt af sløret bliver løft sammen med ledelsens forventninger. Det er dog vist for tidligt at måle nogen reel omsætning før Q3.
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bliver spændende på torsdag
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