Genmab — December 2025
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Raul Cordoba, MD, PhD #EHA2026 (@DrRaulCordoba) on X
Chea. Epcoritamab + R-miniCHOP in elderly 1L DLBCL. Very old population. But age was the main reason for not giving full dose of anthracycline in 97%. Lacking of frailty evaluation with geriatric assessment. #ASH25 #hematology #lymsm #geriheme https://t.co/D7yGlhWEm1
X (formerly Twitter) (x.com)
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Genmab Presents Pivotal Phase 3 Data from EPCORE
FL-1 Trial Demonstrating Clinical Benefit of EPKINLY (epcoritamab-bysp) in Combination with Rituximab and Lenalidomide (R2) in Patients with Relapsed or Refractory Follicular Lymphoma https://ir.genmab.com/news-releases/news-release-details/genmab-presents-pivotal-phase-3-data-epcorer-fl-1-trial -
Det er stærke data fra EPCORE FL-1-studie. De demonstrerer klare kliniske fordele ved epcoritamab i kombination med rituximab og lenalidomid (R²) sammenlignet med R² alene som standardbehandling for patienter med relapsed/refractory FL efter mindst én tidligere linje. Sikkerhedsprofilen er håndterbar og i tråd med monoterapi.Samlet set balancerer sikkerheden de høje effektresultater godt, hvilket gør behandlingen velegnet til udsatte patienter uden at kompromittere livskvalitet markant.
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Kan være game changer i relapsed FL. Det ligner en potentiel ny standard i anden linje
Epkinly + R² er markant bedre og længerevarende effekt med acceptabel sikkerhed.
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Godmorgen
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Genmab viser lovende resultater i fase 3-studie med kræftmiddel https://proinvestor.com/investornyt/1390915/genmab-viser-lovende-resultater-i-fase-3-studie-med-kraeftmiddel
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Fra MW "Genmab har fået hævet sit kursmål til 2050 kr. fra 1650 kr. hos JP Morgan.
I samme ombæring fastholdes anbefalingen "neutral", det fremgår af data fra Bloomberg News.
Fredag faldt Genmab-aktien med 1,5 pct. til 2032 kr. Samlet er aktien i Genmab steget 36,2 pct. i år."
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#ASH25 | PRESENTATION
Lori Leslie shares 3-year results from the phase Ib/II EPCORE NHL-2 trial, of 1L epcoritamab with rituximab + lenalidomide (Arm 6; n = 41) and epcoritamab maintenance monotherapy following SOC (Arm 7; n = 19), in patients with FL. https://x.com/lymphomahub/status/1997759594098295276 -
December 7, 2025
EPCORE FL-1: Adding Epcoritamab to R2 Delivers “New Benchmark” in Second-Line Follicular Lymphoma https://www.ajmc.com/view/epcore-fl-1-adding-epcoritamab-to-r2-delivers-new-benchmark-in-second-line-follicular-lymphoma -
Genmab gør et godt helhedsindtryk med sine studiedata mener Jyske Bank https://proinvestor.com/investornyt/1390946/genmab-gor-et-godt-helhedsindtryk-med-sine-studiedata-mener-jyske-bank
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RedirecTT-1 Talquetamab (GPRC5D) + Teclistamab (BCMA) - Dual Targeting of Extramedullary Myeloma with Talquetamab and Teclistamab - https://www.nejm.org/doi/full/10.1056/NEJMoa2514752 https://x.com/DrRishabhOnco/status/1997930035827929089
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for those that didn't read genmab's press release, the FL data was also published in the Lancet - Epcoritamab, lenalidomide, and rituximab versus lenalidomide and rituximab for relapsed or refractory follicular lymphoma (EPCORE FL-1): a global, open-label, randomised, phase 3 trial https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)02360-8/fulltext
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