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  4. Genmab — December 2024

Genmab — December 2024

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #74

    true on Tec,
    but that development can't be stopped- if it isn't Tec then another BCMA engager; at least genmab gets a royalty now

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #75

      and if SuperDara works maybe they can also make a SuperTec 😉

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      • SolsenS Offline
        SolsenS Offline
        Solsen
        wrote on sidst redigeret af
        #76

        Some slides on tec https://x.com/bertrandbio/status/1865821047708156414?s=61&t=JauvgjicW74kU8sNN3xEFA

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        • SolsenS Offline
          SolsenS Offline
          Solsen
          wrote on sidst redigeret af
          #77

          https://x.com/bertrandbio/status/1865821050090696978?s=61&t=JauvgjicW74kU8sNN3xEFA https://x.com/bertrandbio/status/1865823457973608495?s=61&t=JauvgjicW74kU8sNN3xEFA https://x.com/bertrandbio/status/1865823791076487442?s=61&t=JauvgjicW74kU8sNN3xEFA

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          • P Offline
            P Offline
            ProinvestorNEWS
            wrote on sidst redigeret af
            #78

            Servicemeddelelse: Efter serverskiftet i weekenden kører vores newsfeed desværre ikke pt. Vi arbejder på at få løst problemet.

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            • SolsenS Offline
              SolsenS Offline
              Solsen
              wrote on sidst redigeret af
              #79

              Tror godt at JNJ udnytter optionen, hvis erzo differentierer sig fra faspro. Der er usikkerhed til prisen de kan forlange for faspro efter patentudløb på dara. Men kommer det prispres ikke fra US m.v. så vil der ikke blive solgt meget erzo før faspros patent udløber.

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              • W Offline
                W Offline
                w
                wrote on sidst redigeret af
                #80

                hvad er royalty satsen på Tec?

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                • S Offline
                  S Offline
                  Sukkeralf
                  wrote on sidst redigeret af
                  #81

                  Formentlig 6-8%

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                  • G Offline
                    G Offline
                    GeorgeBest
                    wrote on sidst redigeret af
                    #82

                    Royalty på tec og tal er low single digit. Nærmere 4%. Tec og tal indeholder kun et molekyle fra Genmab.Det
                    er kun rybrevant der har high single digit, da begge molekyler kommer fra Genmab.

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                    • D Offline
                      D Offline
                      deleted-user
                      wrote on sidst redigeret af
                      #83

                      Det er nu "a mid-single digit royalty"

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                      0
                      • D Offline
                        D Offline
                        deleted-user
                        wrote on sidst redigeret af
                        #84

                        "mid single digit"

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                        0
                        • G Offline
                          G Offline
                          gentogen
                          wrote on sidst redigeret af
                          #85

                          Begge er ifølge årsrapporten mid-single digit (hvilket selvfølgelig godt kan være 4)

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                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #86

                            GB hvor ved du fra Genmab har leveret den ene arm til Tec eller Tal?

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                            0
                            • S Offline
                              S Offline
                              Sukkeralf
                              wrote on sidst redigeret af
                              #87

                              Gentogen står der i årsrapporten noget om forskellen på den oprindelige aftale og udvidelsen et år eller to senere?

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #88

                                small new University trial- Epcoritamab and Lenalidomide in Treating Patients With Refractory or Relapsed Immunodeficiency-Related Large B-Cell Lymphoma https://clinicaltrials.gov/study/NCT06723457

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                                • G Offline
                                  G Offline
                                  gentogen
                                  wrote on sidst redigeret af
                                  #89

                                  Det tror jeg ikke: Under our agreement with Janssen, Genmab is eligible to receive milestones and receives royalties between 8% and 10% on net sales of RYBREVANT, a mid-single digit royalty on net sales of TECVAYLI, and a mid-single digit royalty on net sales of TALVEY, all of which are subject to a reduction of such royalty payment in countries and territories where there are no relevant patents (as defined in the agreement), among other reductions.

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                                  • G Offline
                                    G Offline
                                    GeorgeBest
                                    wrote on sidst redigeret af
                                    #90

                                    Sukkeralf, det er oplyst flere gange på konferencer etc. Derfor forskellen på royalty procent I forhold til Rybrevant.

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                                    • SolsenS Offline
                                      SolsenS Offline
                                      Solsen
                                      wrote on sidst redigeret af
                                      #91

                                      "The unprecedented durability of response seen in these data reinforce the potential of epcoritamab to become a core therapy for the treatment of multiple B-cell malignancies to benefit more patients," said Dr. Judith Klimovsky https://ml-eu.globenewswire.com/Resource/Download/5d2ab26b-5092-40d5-85c9-b653ab612acd

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #92

                                        same from AbbVie
                                        "More first-line treatments for diffuse large B-cell lymphoma are needed, especially for patients with aggressive disease markers that may impact the efficacy of current standard first-line therapies," said Lorenzo Falchi, M.D., Lymphoma Specialist, Department of Medicine, Memorial Sloan Kettering Cancer Center. "The durable responses observed in the study suggest significant potential for this first-line epcoritamab-based combination."

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                                        0
                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #93

                                          Link Preview Image
                                          Two Data Analyses From Clinical Trials Show Epcoritamab (DuoBody® CD3xCD20) Induces Durable Complete Reponses As Monotherapy and Combination Treatment in Patients With Diffuse Large B-Cell Lymphoma

                                          Data presented at the 66th Annual Meeting and Exposition of the American Society of Hematology (ASH) NORTH CHICAGO, Ill., Dec. 9, 2024 /PRNewswire/ -- AbbVie (NYSE: ABBV) today announced new...

                                          favicon

                                          AbbVie News Center (news.abbvie.com)

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