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  4. Genmab — Oktober 2024

Genmab — Oktober 2024

Planlagt Fastgjort Låst Flyttet Genmab
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  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #875

    Revitope press release - Revitope Enters into a License Agreement for Next-generation T Cell Engagement Technology https://www.prnewswire.com/news-releases/revitope-enters-into-a-license-agreement-for-next-generation-t-cell-engagement-technology-302290430.html?utm_source=dlvr.it&utm_medium=twitter

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #876

      novartis q3-2024-earnings-call-transcript https://www.fool.com/earnings/call-transcripts/2024/10/29/novartis-ag-nvs-q3-2024-earnings-call-transcript/ Kesimpta -We're annualizing now well above $3 billion, and have the opportunity, I think, to well exceed our $4 billion peak sales guidance to date.

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      • StockBullS Offline
        StockBullS Offline
        StockBull
        wrote on sidst redigeret af
        #877

        EL 15.12: seems they have been working on this since 2021. Are part 1 completed and now part 2 . https://institut-curie.org/clinical-trial/gct1047-01

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        • StockBullS Offline
          StockBullS Offline
          StockBull
          wrote on sidst redigeret af
          #878

          8 Super Gems Found, Out of 100+ Stocks (Quality + Hyper Growth + Deep Value + High Cashflow) https://www.youtube.com/watch?v=ude3-6H8GtM

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #879

            But they stopped recruiting. it is possible they'll get all the data they need to proceed with the 179 patients currently recruited, but i doubt that. But would very much like to hear that i am wrong here next week.

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            • StockBullS Offline
              StockBullS Offline
              StockBull
              wrote on sidst redigeret af
              #880

              It seems they haven't fully integrated the AI technology that was anticipated to streamline processes.

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              • StockBullS Offline
                StockBullS Offline
                StockBull
                wrote on sidst redigeret af
                #881

                Probably its only on future trials. Wonder if they can use less patients now that they use AI

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                • StockBullS Offline
                  StockBullS Offline
                  StockBull
                  wrote on sidst redigeret af
                  #882

                  Implementeringen af AI i kliniske forsøg kan faktisk påvirke rekrutteringsstrategierne for patienter. AI-teknologier kan muligvis strømline processer, forbedre målretning af patienter eller forbedre dataanalyse, hvilket potentielt kan føre til mere effektiv rekruttering.

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                  • StockBullS Offline
                    StockBullS Offline
                    StockBull
                    wrote on sidst redigeret af
                    #883

                    Hvis AI-værktøjerne dog ikke er blevet ordentligt integreret, eller hvis der har været problemer med at målrette den rigtige patientpopulation, kan det også bidrage til lavere rekrutteringsnumre. Desuden, hvis studiekravene er blevet mere strenge på grund af AI-drevne indsigter, kan det begrænse antallet af kvalificerede deltagere. Det ville være nyttigt at se efter specifik information i de kommende opdateringer for at forstå AI's indvirkning på rekrutteringen til GEN1047.

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                    • StockBullS Offline
                      StockBullS Offline
                      StockBull
                      wrote on sidst redigeret af
                      #884

                      Welcome to Genmab

                      favicon

                      (www.genmab.com)

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                      • StockBullS Offline
                        StockBullS Offline
                        StockBull
                        wrote on sidst redigeret af
                        #885

                        Optimizing clinical trials
                        Clinical trials are essential for evaluating the safety and efficacy of new treatments. Yet they can be lengthy, costly and challenging. Genmab is using AI to optimize the clinical trials process, applying the technology to help identify suitable patient populations, streamline the recruitment process, and design and execute trials more efficiently.

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #886

                          There was a TV abstract at the 62nd Annual Meeting of the Japanese Society of Clinical Oncology - Tisotumab Vedotin vs Chemotherapy in Japanese Patients With Recurrent/Metastatic Cervical Cancer From
                          the Phase 3 innovaTV 301 Study.

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #887

                            translating this https://medical.nikkeibp.co.jp/leaf/all/cancernavi/news/202410/586322.html gave some results , best in english- During the median follow-up period of 13.7 months, the median OS was 15.0 months (95% CI: 9.7-NE) in the TV group and 8.5 months (95% CI: 6.8-10.6)

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #888

                              If i am not mistaken, the data we had seen before was 11.5 vs 9.5 months OS (with a slightly shorter follow up though), so this data seems better at first glance

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                              • StockBullS Offline
                                StockBullS Offline
                                StockBull
                                wrote on sidst redigeret af
                                #889

                                Næste uge bliver meget interessant med Novo, Genmab og det amerikanske valg

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                                • L Offline
                                  L Offline
                                  lahn1
                                  wrote on sidst redigeret af
                                  #890

                                  visse-vasse 😉

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                                  • StockBullS Offline
                                    StockBullS Offline
                                    StockBull
                                    wrote on sidst redigeret af
                                    #891

                                    Det jo Genmab selv der siger de bruger AI til at optimere clinical trials 🙂

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                                    • StockBullS Offline
                                      StockBullS Offline
                                      StockBull
                                      wrote on sidst redigeret af
                                      #892

                                      men ja p.t kan vi kun gætte. også derfor Jan skal længere frem i skoene for opdatere på alle fronter

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                                      • L Offline
                                        L Offline
                                        lahn1
                                        wrote on sidst redigeret af
                                        #893

                                        Bryder mit hoved med Gen1046 completion data, og vil gerne tro på at datoen er udsat fordi patienterne lever længere end de oprindeligt havde regnet med. Men det kan vel også have at gøre med deres mitigation plan, som nu tilsiger at visse patienter skal have pauser for a ikke udmatte T-cellerne. Det sidste er også nyt ift den oprindelige plan og kunne sagtens være grundet til den udsatte dato uden at være negativt.

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                                        • J Offline
                                          J Offline
                                          JKY_VH
                                          wrote on sidst redigeret af
                                          #894

                                          Ja, det er i givet fald et positivt "problem", men er der noget til hinder for at give en status på forsøget eller vil det ikke give mening af en eller anden årsag?

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