Genmab — Maj 2024
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Genmab updated it's website to include ProfoundBio, including the pipeline https://www.genmab.com/antibody-science/pipeline
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Video: Den Europæiske Centralbank ECB sætter formentlig renten ned i næste uge, men hvor meget? Hør også om NVIDIA, Mærsk og DSV's interesse for at købe DB Schenker, samt om de to danske biotekselskaber Zealand Pharma, Novo Nordisk og Genmab. https://proinvestor.com/boards/120672
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In 2024, 2,001,140 new cancer cases and 611,720 cancer deaths are projected to occur in the United States I did not realize cervical cancer was also still growing https://x.com/CACancerJournal/status/1795859675071529225
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Dem som ikke læste gentogens link så er det en spændende artikel om dara resistente patienter. https://portal.findresearcher.sdu.dk/en/publications/resistance-to-daratumumab-in-patients-with-multiple-myeloma
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CancerNetwork
@CancerNetwrk
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@DrJulieVose
discusses her upcoming
@ASCO
presentation on epcoritamab in R/R follicular lymphoma. #lymsm #ASCO24 https://x.com/CancerNetwrk/status/1796134464667717885 -
Kort video....
Pharma- og biotekopdatering uge 22 | Genmab, Zealand Pharma og Novo Nordisk https://proinvestor.com/boards/120686 -
ASCO er noget atypisk for Genmab's kursudvikling i år..... I hvert fald de seneste år, har aktien i hvert fald steget pænt op imod ASCO, for efterfølgende at blive ramt af de ledeste tømmermænd i form af kursfald..... Tør vi håbe på at det bliver lige omvendt i år?.... For mit vedkommende er det en ren gyser
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Børsen gentager verdens 10 bedst sælgende lægemidler. 3. Ozempic 14 mia. USD, 10. Darzalex 9,7 mia. USD https://borsen.dk/nyheder/virksomheder/se-listen-novo-storsaellert-blandt-de-bedst-saelgende-i-verden?b_source=borsen&b_medium=row_0&b_campaign=list_1
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Med hensyn til spørgsmålene i går om Hexa38, så er bedste kilde indtil videre vist nok statig artiklen fra the Lancet: https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00228-1/fulltext
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We’re advancing our DuoBody platform technology with the goal to unlock the potential of #bispecific antibody research, as we work to transform how cancer is treated. Watch the video below to learn more about our technology. #ASCO24" https://x.com/Genmab/status/1796542979273809922?t=SBZtpWL3ba-xUGouEiqH3Q&s=19 -
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Enhanced CDC: Hexabody-CD38 is engineered to enhance complement-dependent cytotoxicity (CDC) through hexamerization. This increased CDC activity can overcome the reduced sensitivity to complement-mediated lysis seen in DARA-resistant patients due to the upregulation of complement inhibitory proteins (CD55 and CD59).
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Broader Mechanisms: Hexabody-CD38 not only enhances CDC but also maintains other mechanisms of action such as antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and apoptosis induction. These multiple mechanisms provide a robust anti-tumor activity, which is beneficial for overcoming resistance
ja ja ved godt det nok ikke holder i virkeligheden. men her er hvad Chat GPT 4.0 siger om emnet i bullet pointsHello! It looks like you're interested in this conversation, but you don't have an account yet.
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