Genmab — December 2023
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ESMO Immuno-Oncology 2023 Poster online- HexaBody-OX40, a novel Fc_ receptor crosslinking-independent OX40-targeting antibody, exhibits agonistic activity in vitro and antitumor activity in vivo https://cslide.ctimeetingtech.com/immuno23hybrid/attendee/confcal/presentation/list?q=148P+ "A first-in-human clinical trial is planned " I am assuming this is the #6 in the BioNTech cooperation.
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ESMO Immuno-Oncology 2023 Poster - Safety and Antitumor Activity of GEN1042 in Combination with Pembrolizumab _ Chemotherapy in Solid Tumors: Phase 2b Dose-Expansion Trial in Progress https://cslide.ctimeetingtech.com/immuno23hybrid/attendee/confcal/presentation/list?q=160TiP+
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Genmab hæves til "køb" hos schweizisk storbank https://www.proinvestor.com/investornyt/1086822/genmab-haeves-til-kob-hos-schweizisk-storbank
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"OX40 has been implicated in the pathologic cytokine storm associated with certain viral infections, including the H5N1 bird flu" If it doesn't work in solid tumors ; Biontech knows how to create vaccins
https://en.wikipedia.org/wiki/CD134 -
I find it comforting that BioNTech is willing to try the second Hexabody. After all, the technology has not yet been proven. But it would not surprise me if they have also seen the data on Hexabody-DR5/DR5 . Doubt they are allowed to see Hexabody-CD38 data early though.
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Johnson & Johnson’s prescription for growthhttps://www.proinvestor.com/investornyt/1087102/johnson-amp-johnsonrsquos-prescription-for-growth
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"Key pharmaceuticals like Darzalex, Carvykti, and Stelara are pivotal revenue drivers, illustrating J&J's steadfast commitment to developing and delivering life-altering treatments. These flagship drugs continue to showcase robust market demand, underpinning the company's revenue expectations"
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