Biotek-snakken — August 2020
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er der nogen der kender til FGEN?. FGEN har fået godkendt et produkt i Kina (Roxadustat) som er first in class og er til behandling af kronisk nyresygdom. Ansøgning ligger også hos FDA. Det kunne se ud til at blive en Blockbuster og har utroligt mange penge i kassen også.
MVH Rasmus
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God morgen.
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Q: Hi, and thanks for taking the question. Could you comment a little bit on infector ADC with iconic that we'll be going into the clinic shortly? Seattle Genetics has reported some positive data with its ADC tissue factor targeting agent. Are you thinking about cervical cancer, ovarian cancer or do you go with an Alzheimer's population prior to picking your indication?
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A: Yes. So, I mean you're correct, right? This is – there is clinical proof-of-concept for tissue factor targeting ADCs. The iconic version of this was compelling to us because of some differentiation that it provided. It could be premature for me to speculate or to discuss what our clinical strategy might be at this point. But again, later in the year, we anticipate presenting data, preclinical data, obviously, on this agent at a meeting and when we have that information.
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Så rart denne ADC når IND stadiet, men igen må jeg sige at jeg er skuffet over at Zymeworks ikke har lukket andre aftaler på deres ADC.........og at det trækker ud med data på ZW49, som jeg tidligere har nævnt. Lad os håbe på 1 eller 2 IND mere fra Zymeworks partnere i år !
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Lahn1 - ved seneste Zymeworks opdatering var det samme tidslinie for ZW25 i 1. linie GEA, men den har tidligere hedder omkring årsskiftet. Så det er jo ikke nogen katastrofe at det bliver nogle måneder forsinket (og muligvis alene grundet COVID-19).
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