Bavarian Nordic — August 2024
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Gaci har 2,5 mia $ i Day Zero Financing Facility men dette skal bruges på mange ting end kun mpox.
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Emergent BioSolutions steg 18 % efter FDA nyheden kom men er faldet tilbage til sit oprindelig niveau. https://qz.com/emergent-biosolutions-mpox-vaccine-fda-1851636851
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WHO siger at endelig godkendelse af vaccine kommer om 2 uger men at de store indkøber har lov til at købe ind. https://www.reuters.com/world/africa/who-chief-says-mpox-vaccines-due-arrive-dr-congo-next-few-days-2024-08-30/
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Godmorgen
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God morgen
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CNBC’s TV program “Fast Money” havde et indslag om Emergent Biosolutions kursudviklngen igår ovenpå FDA begrænset godkendelse af selskabets Mpox vaccine - https://youtu.be/ywQJTL8l05s
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Og typiske amerikanske - åh det er over på 3-4 uger så “what is the big deal” - Jansen du kommer Jo Koke til
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Jeg prøver lige den sidste sætning efter bindestregen igen
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- Ja men du kommer jo til at se grim ud rent kometisk! Her er ingen tanke på at mennesker dør af sygdommen og 80 % af dem er børn og unge.
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Og TV indslaget har ingen diskussion af væsentlig forskelle i både bivirkninger og godkendelse status mellem Emergents og Bavarian Nordics vaccine.
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ES: tyder på der er nyheder på vej fra Mexico: https://llk.dk/ik8f7g
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Her er em kost in use sammenlign baseret på mva-bn og acem2000 i usa. Regnestykket ser nok anderledes ud i Afrika. Ser ud til ren vaccine acam2000 koster 4.87 usd pr dose, det kon måske spille ind hvis man skal donere større mængder https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://www.tandfonline.com/doi/pdf/10.1080/23793406.2016.1171944&ved=2ahUKEwiajLmZ0Z6IAxVYEhAIHa87OwsQFnoECBEQAQ&usg=AOvVaw2wcXfUYtEdUy8vwf8DV9Al
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Nu begynder BN’s vaccine at ankomme i Afrika - https://www.alphagalileo.org/es-es/Item-Display-es-ES/ItemId/249452?returnurl=https://www.alphagalileo.org/es-es/Item-Display-es-ES/ItemId/249452
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8 critical points:
️ACAM2000 is second-generation vaccine that contains a live vaccinia virus that replicates efficiently in humans (#JYNNEOS and LC16 are third-generation vaccines that do not replicate).️The US has 200 million doses stockpiled.️It needs to be administered by using a bifurcated steel needle, dipped into the vaccine, and then introduced into the upper arm multiple times.️The vaccine causes a Vaccinia Pox infection , hence it is not given to the immunocompromised.️Th -
The vaccine may cause myocarditis and pericarditis.
️ Serious health problems, including life-threatening, can also occur in unvaccinated people who are accidentally infected by someone who has recently received the vaccine.️I’m unsure who the #FDA intends to give this vaccine to. The developed world won’t accept it, and Africa can’t use it safely (unless the situation is dire)?
️?️️The labelling will be for those at high risk of Mpox infection, where there is no alternative.
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