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  4. Genmab — September 2025

Genmab — September 2025

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
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    E_L
    wrote on sidst redigeret af
    #62

    – the combination of ADC with immunotherapy, which they also spoke about earlier and he mentioned GEN1042 and 46 as examples again that could be combined with ADCs

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    • S Offline
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      Sukkeralf
      wrote on sidst redigeret af
      #63

      Hopefully GEN1042 will deliver good data later this year.

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      • E Offline
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        E_L
        wrote on sidst redigeret af
        #64

        that would be a nice surprise, as expectations are low...

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        • W Offline
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          w
          wrote on sidst redigeret af
          #65

          is it
          TA or FA that is driving the current direction?

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          • E Offline
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            E_L
            wrote on sidst redigeret af
            #66

            TA AND FA AND common sense 😉

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            • W Offline
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              w
              wrote on sidst redigeret af
              #67

              what has changed in FA since april?

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              • E Offline
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                E_L
                wrote on sidst redigeret af
                #68

                you follow this chat every day w, i don't think i need to make you a summary 😉 check the august interim report and add the latest epkinly data and Rina-s FDA breakthroughTD

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                  E_L
                  wrote on sidst redigeret af
                  #69

                  RAINFOL-03. New:
                  Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer https://clinicaltrials.gov/study/NCT07166094

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                    ProinvestorNEWS
                    wrote on sidst redigeret af
                    #70

                    Genmabs kursmål løftes 10 pct. hos JPMorgan https://proinvestor.com/investornyt/1360289/genmabs-kursmal-loftes-10-pct-hos-jpmorgan

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                    • V Offline
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                      Vitus
                      wrote on sidst redigeret af
                      #71

                      Er dagens kursstigning gennembruddet…

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                      • E Offline
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                        E_L
                        wrote on sidst redigeret af
                        #72

                        PALOMA-2 Study: Subcutaneous Amivantamab Every 4 Weeks Plus Lazertinib Shows High Response Rate in EGFR-Mutated NSCLC https://www.iaslc.org/iaslc-news/press-release/paloma-2-study-subcutaneous-amivantamab-every-4-weeks-plus-lazertinib

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                          E_L
                          wrote on sidst redigeret af
                          #73

                          Blood: Fixed-Duration Epcoritamab Plus R2 Drives Favorable Outcomes in Relapsed or Refractory Follicular Lymphoma https://ashpublications.org/blood/article/doi/10.1182/blood.2025029909/547148/Fixed-Duration-Epcoritamab-Plus-R2-Drives

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                            E_L
                            wrote on sidst redigeret af
                            #74

                            similar to data we saw last year ASH i think, later data cut off, ORR and complete response (CR) rate were 96% and 88%

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                              E_L
                              wrote on sidst redigeret af
                              #75

                              " With a median follow-up of >2 years, the combination of epcoritamab and R2 demonstrated clinically meaningful antitumor activity, with CR rates that, to our knowledge, are higher than any previously published for other bispecific antibody–based regimens in R/R FL"

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                                E_L
                                wrote on sidst redigeret af
                                #76

                                "Analyses based on pLOT showed that the CR rate was higher in the 2L group compared with the group receiving epcoritamab plus R2 in the third line or later, suggesting an advantage to using epcoritamab regimens earlier. Most patients with a poor prognosis, such as those with primary refractory or double-refractory disease, whose FL is typically resistant to common therapies including rituximab, had a CR with epcoritamab plus R2."

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                                • E Offline
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                                  E_L
                                  wrote on sidst redigeret af
                                  #77

                                  Scancell Business Update -Second commercial licence with Genmab for SC2811 secured for $6 million in total upfront payments and up to $630 million in potential milestones and low-single digit royalties
                                  Development of the first Genmab partnered SC129 remains on track with further milestones payments anticipated in the near-term. https://www.globenewswire.com/news-release/2025/09/11/3148321/0/en/Scancell-reports-Business-Update-and-Financial-Results-for-the-Year-Ended-30-April-2025.html

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                                    lahn1
                                    wrote on sidst redigeret af
                                    #78

                                    EL, you have the best News Service avail. Keep them coming 🙂

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                                      lahn1
                                      wrote on sidst redigeret af
                                      #79

                                      Jeg synte sgu det køre for Gmab for tiden, det wr godt nok en lettelse oven på alle de måneder med konstant nedgang i prisen. Med en PE under 15 er der luft til mere stigning som helt sikkert kommer med forventede gode data i 2H

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                                        Plimsoller
                                        wrote on sidst redigeret af
                                        #80

                                        Den er steget omkring 55% siden starten / midten af april, så det er absolut godkendt - også selvom det var et billigt udgangspunkt.

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                                        • E Offline
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                                          E_L
                                          wrote on sidst redigeret af
                                          #81

                                          Rinatabart sesutecan
                                          on the EMA PDCO agenda for a Product Specific Waiver
                                          in Endometrial cancer (for lahn 😉 )

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                                          0

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