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  4. Genmab — September 2025

Genmab — September 2025

Planlagt Fastgjort Låst Flyttet Genmab
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  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #34

    did we know this -14-2-25 Centessa granted to Genmab an exclusive worldwide license to leverage the Company’s proprietary LockBody platform to research products against up to three undisclosed targets during a multi-year research period, with an option to take up to three exclusive commercial licenses for worldwide development and commercialization of products against each selected target. https://investors.centessa.com/node/10006/html

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #35

      Genmab will be conducting all research and development activities under the License Agreement and the products may combine Centessa’s LockBody technology with Genmab’s proprietary antibody technologies. The LockBody technology platform is designed to improve the therapeutic index of therapies by allowing targeted conditional activation of potent cell killing mechanisms in diseased tissue only.

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #36

        Under the terms of the License Agreement, Centessa will receive an upfront payment of $15 million and option exercise fees potentially totaling up to an additional $15 million and is eligible to receive potential payouts of approximately $230 million in development, regulatory and sales milestones per product, as well as tiered royalties ranging in the mid-single digits on annual global net licensed product sales.

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        • L Offline
          L Offline
          lahn1
          wrote on sidst redigeret af
          #37

          Nogen der har et bud på hvilke targets Gmab vil gå efter med Lockbody. CD3 i solide tumor noget 4-1BB ? Der er vel ingen af deres eksisterende kandidater der vil have fordel af at blive bindet sammen med Lockbody ?

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          • L Offline
            L Offline
            lahn1
            wrote on sidst redigeret af
            #38

            bundet

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            • P Offline
              P Offline
              ProinvestorNEWS
              wrote on sidst redigeret af
              #39

              Pharma og biotek har længe været kursmæssigt underdrejet - selv store, sunde pharma-selskaber. Mange investorer har søgt over i f.eks. amerikanske tech-aktier. Men er den tendens ved at vende? Er bunden fundet for pharma og biotek? Skal det bare gå opad nu? Det spørgsmål giver Helge Larsen sit svar på i denne ugekommentar, hvor han også kommer ind på teknisk analyse og algoritmehandels rolle på aktiemarkedet. Kort video: https://proinvestor.com/boards/128230

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              • P Offline
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                ProinvestorNEWS
                wrote on sidst redigeret af
                #40

                Genmabs Darzalex nærmer sig ny eksamen i USA https://proinvestor.com/investornyt/1358101/genmabs-darzalex-naermer-sig-ny-eksamen-i-usa

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #41

                  From
                  Stockwatch DK
                  @StockwatchDK
                  Nordea says that it is worth noting that Epkinly currently – when used in patients with third-line DLBCL (3L R/R DLBCL) – requires the first dose to be administered during hospitalization. - However, with the new data in hand, Nordea expects Genmab to seek to update the product’s package insert, further differentiating Epkinly from its competitors. -

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #42
                    • Nordea says: In our view, this could also mean that Epkinly is generally used earlier in the treatment pathway as treating physicians and centers become comfortable with outpatient dosing.
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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #43

                      RYBREVANT® (amivantamab-vmjw) plus LAZCLUZE® (lazertinib) offers unmatched survival benefit in a chemotherapy-free regimen, reducing treatment resistance vs osimertinib in first-line EGFR-mutated NSCLC https://www.jnj.com/media-center/press-releases/rybrevant-amivantamab-vmjw-plus-lazcluze-lazertinib-offers-unmatched-survival-benefit-in-a-chemotherapy-free-regimen-reducing-treatment-resistance-vs-osimertinib-in-first-line-egfr-mutated-nsclc

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                      • P Offline
                        P Offline
                        ProinvestorNEWS
                        wrote on sidst redigeret af
                        #44

                        Ugens danske Vindere & Tabere: Genmab, Ørsted og Norden https://proinvestor.com/investornyt/1358883/ugens-danske-vindere-amp-tabere-genmab-oslashrsted-og-norden

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                        • P Offline
                          P Offline
                          peter12
                          wrote on sidst redigeret af
                          #45

                          En del om Rina-S ved 18:17 og 30:00 https://uniteforher.com/herlibrary/video/updates-in-ovarian-cancer/

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                          • A Offline
                            A Offline
                            Aps_invest
                            wrote on sidst redigeret af
                            #46

                            Genmab: Partner har lovende resultater med middel mod lungekræft
                            8:24
                            Genmabs partner Johnson & Johnson har offentliggjort lovende resultater med sit lungekræftmiddel Rybrevant som førstebehandling i kombination med lægemidlet Lazcluse. Kombinationen tegner bedre for patienternes overlevelse end lægemidlet Osimertinib.

                            Det fremgår af en meddelelse fra Johnson & Johnson.

                            Genmab modtager høje encifrede og op til tocifrede royalties fra Johnson & Johnsons salg af Rybrevant, der solgte for 320 mio

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #47

                              Overall Survival with Amivantamab–Lazertinib in EGFR-Mutated Advanced NSCLC https://www.nejm.org/doi/full/10.1056/NEJMoa2503001

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                              • P Offline
                                P Offline
                                ProinvestorNEWS
                                wrote on sidst redigeret af
                                #48

                                Novo og europæiske sundhedskollegaer holdes nede af advarsel fra Morgan Stanleyhttps://proinvestor.com/investornyt/1359075/novo-og-europaeiske-sundhedskollegaer-holdes-nede-af-advarsel-fra-morgan-stanley

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                                • G Offline
                                  G Offline
                                  gdn55
                                  wrote on sidst redigeret af
                                  #49

                                  Der er da ingen i USA,
                                  der har brug for medicin, så længe vores kære Donald har det godt

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                                  • J Offline
                                    J Offline
                                    JKY_VH
                                    wrote on sidst redigeret af
                                    #50

                                    og hvis de har er det Bidens skyld 🙂

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #51

                                      Data published in The New England Journal of Medicine demonstrate RYBREVANT® (amivantamab-vmjw) plus LAZCLUZE® (lazertinib) is re-setting survival expectations in first-line EGFR-mutated lung cancer
                                      September 8, 2025 https://innovativemedicine.jnj.com/us/news-center/oncology/data-published-in-the-new-england-journal-of-medicine-demonstrate-rybrevant-amivantamab-vmjw-plus-lazcluze-lazertinib-is-re-setting-survival-expectations-in-first-line-egfr-mutated-lung-cancer

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                                      • SolsenS Offline
                                        SolsenS Offline
                                        Solsen
                                        wrote on sidst redigeret af
                                        #52

                                        Summit nåede ikke endpoint i OS med deres vegf x pd-1 i NSCLC https://www.investors.com/news/technology/summit-therapeutics-stock-pd-1-vegf-lung-cancer-treatment/?src=A00220

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #53

                                          in 5minutes Sep 9, 2025 7:45 AM EDT
                                          Morgan Stanley 23rd Annual Global Healthcare Conference https://ir.genmab.com/events-presentations

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