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Kollaps
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  4. Genmab — Maj 2025

Genmab — Maj 2025

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #247

    ASCO 25 A phase 3, open-label, randomized study of rinatabart sesutecan (Rina-S) vs investigator’s choice (IC) of chemotherapy in patients with platinum-resistant ovarian cancer (PROC) https://meetings.asco.org/abstracts-presentations/252407

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #248

      ASCO 25 Novel analysis of 3-y results from the pivotal EPCORE NHL-1 study: Outcomes in patients (pts) with relapsed/refractory large B-cell lymphoma (R/R LBCL) and complete response (CR) at 2 y with epcoritamab (epcor) monotherapy. https://meetings.asco.org/abstracts-presentations/246029

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #249

        ASCO 25 First data from phase 1b/2 EPCORE NHL-4: Epcoritamab (Epcor) in Chinese patients (Pts) with relapsed or refractory diffuse large B-cell lymphoma (R/R DLBCL). https://meetings.asco.org/abstracts-presentations/246176

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        • SolsenS Offline
          SolsenS Offline
          Solsen
          wrote on sidst redigeret af
          #250

          Spændende resultater i endometrial cancer. Her ser 100 mg at være tilstrækkelig og med et dødsfald i 120 mg gruppen. Ikke optimalt men svære pts at behandle.

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          • SolsenS Offline
            SolsenS Offline
            Solsen
            wrote on sidst redigeret af
            #251

            Rina-S har ikke Elaheres achilleshæl bivirkninger “ No signals of ocular toxicity, neuropathy, or interstitial lung disease were observed”

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            • J Offline
              J Offline
              JKY_VH
              wrote on sidst redigeret af
              #252

              Fra MW "Genmab vil over flere omgange præsentere data fra sin pipeline i forbindelse med årsmødet his American Society of Clinical Oncology (ASCO) i starten af juni.

              Præsentationerne inkluderer den første offentliggørelse af resultater fra et fase 1/2-studie med Rina-S til behandling af kræft i livmoderen."

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #253

                For Ovarian Cancer there was a big difference between the 100 and 120mg dose, 120mg much better. Safety for endometrial seems slightly better?

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #254

                  Johnson & Johnson showcases latest advancements in cancer innovation with more than 70 clinical and real-world studies at ASCO and EHA https://www.jnj.com/media-center/press-releases/johnson-johnson-showcases-latest-advancements-in-cancer-innovation-with-more-than-70-clinical-and-real-world-studies-at-asco-and-eha

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #255

                    Redburn lowers target price for Genmab to DKK 2,700 (2,750), reiterates buy recommendation (part of the Rothschild group)

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #256

                      How Insourcing Transformed Antibody Manufacturing Success https://bioprocessupdates.com/upstream/how-insourcing-transformed-antibody-manufacturing-success/

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #257

                        perplexity analysis Rina-S...not sure if this link will work for others...
                        : https://www.perplexity.ai/search/results-how-does-this-new-data-YPc0_alLR5iBhcEc4MOBsw

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                        • B Offline
                          B Offline
                          bikube
                          wrote on sidst redigeret af
                          #258

                          Virker fint her.

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                          • SolsenS Offline
                            SolsenS Offline
                            Solsen
                            wrote on sidst redigeret af
                            #259

                            Dejlig sætning “If these results are confirmed in larger, longer-term studies, Rina-S could become a best-in-class option for this difficult-to-treat population”

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                            • SolsenS Offline
                              SolsenS Offline
                              Solsen
                              wrote on sidst redigeret af
                              #260

                              Thanks EL 🙂

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                              • G Offline
                                G Offline
                                gentogen
                                wrote on sidst redigeret af
                                #261

                                Thanks. Top nice...

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                                • SolsenS Offline
                                  SolsenS Offline
                                  Solsen
                                  wrote on sidst redigeret af
                                  #262

                                  Stort marked for behandling af endometrial cancer https://www.gminsights.com/industry-analysis/endometrial-cancer-treatment-market

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                                  • SolsenS Offline
                                    SolsenS Offline
                                    Solsen
                                    wrote on sidst redigeret af
                                    #263

                                    Mere https://www.businessresearchinsights.com/market-reports/endometrial-cancer-market-119445 Gad vide om Rina-S kunne kombineres med f.eks. Keytruda ? Så kunne en first line kombo nok vise gode resultater. Hvis da ikke mono Rina-S var god alene. Husk Keytruda snart går off patent.

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                                    • J Offline
                                      J Offline
                                      JKY_VH
                                      wrote on sidst redigeret af
                                      #264

                                      Så fik tåben i US lige ødelagt den gode stemning med 50% told på EU-varer fra næste søndag:-(

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                                      • B Offline
                                        B Offline
                                        bikube
                                        wrote on sidst redigeret af
                                        #265

                                        Han e gal.

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                                        0
                                        • J Offline
                                          J Offline
                                          JKY_VH
                                          wrote on sidst redigeret af
                                          #266

                                          bindegal simpelthen

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