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  4. Genmab — April 2025

Genmab — April 2025

Planlagt Fastgjort Låst Flyttet Genmab
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  • L Offline
    L Offline
    lahn1
    wrote on sidst redigeret af
    #238

    $JNJ announced that the EGFR/c-MET bispecific antibody, Rybrevant (amivantamab), has been approved by #China #NMPA for a new label: in combination with carboplatin and pemetrexed for locally advanced or metastatic non-sq NSCLC carry EGFR Ex19del and exon 21 L858R mutation, and disease has progressed during or after treatment with EGFR TKIs.

    The approval is based on data from the MARIPOSA-2 Ph3 study.

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    • L Offline
      L Offline
      lahn1
      wrote on sidst redigeret af
      #239

      Solsen er det den her fra forleden ? https://www.prnewswire.com/news-releases/ivonescimab-in-combination-with-chemotherapy-demonstrates-statistically-significant-and-strongly-positive-results-in-first-line-treatment-of-squamous-non-small-cell-lung-cancer-sq-nsclc-vs-tislelizumab-in-combination-with-chemo-302435143.html

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      • S Offline
        S Offline
        Sukkeralf
        wrote on sidst redigeret af
        #240

        Thanks E L - we await H2 then 🙂

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        • SolsenS Offline
          SolsenS Offline
          Solsen
          wrote on sidst redigeret af
          #241

          Nej alle de nævnte aktier faldt samtidigt midt på dage US-tid.

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          • S Offline
            S Offline
            Sukkeralf
            wrote on sidst redigeret af
            #242

            Nok snarere denne solsen

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            • S Offline
              S Offline
              Sukkeralf
              wrote on sidst redigeret af
              #243

              Link Preview Image
              Akeso wins Chinese approval for cancer drug positioned to rival Merck’s Keytruda

              New data show early hints of the medicine improving patient survival — the gold standard outcome of any cancer study

              favicon

              STAT (www.statnews.com)

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              • SolsenS Offline
                SolsenS Offline
                Solsen
                wrote on sidst redigeret af
                #244

                Tak. Muligvis. Og en konkurrent til Acasunlimab vi skal holde øje med.

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                • SolsenS Offline
                  SolsenS Offline
                  Solsen
                  wrote on sidst redigeret af
                  #245

                  Nok heller ikke selve godkendelsen i Kina. Summit der har samarbejde med Akeso om stoffet falder små 40%. Der må være kommet nogle skuffende data frem.

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                  • SolsenS Offline
                    SolsenS Offline
                    Solsen
                    wrote on sidst redigeret af
                    #246

                    Derfor at Biontech og TIL også falder voldsomt.

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                    • SolsenS Offline
                      SolsenS Offline
                      Solsen
                      wrote on sidst redigeret af
                      #247

                      Måske nogle bivirkninger. Men jeg er ikke helt inde i casen, andet end ved den har være hypet en del.

                      1 Reply Last reply
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                      • S Offline
                        S Offline
                        Sukkeralf
                        wrote on sidst redigeret af
                        #248

                        Ja hvis de alle falder så meget er det næppe den nyhed

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                        • SolsenS Offline
                          SolsenS Offline
                          Solsen
                          wrote on sidst redigeret af
                          #249

                          Man bliver vel generelt nervøs for alle lignende stoffer.

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                          • SolsenS Offline
                            SolsenS Offline
                            Solsen
                            wrote on sidst redigeret af
                            #250

                            Tickerne er TIL, BNTX, SMMT. Alle nede med mindst 20%

                            1 Reply Last reply
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                            • SolsenS Offline
                              SolsenS Offline
                              Solsen
                              wrote on sidst redigeret af
                              #251

                              Her kom svaret https://finance.yahoo.com/news/interim-overall-survival-analysis-requested-185000973.html Hazard ration på OS stiger fra første interim analyse på 0,51 til 0,78 i anden interim analyse.

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                              • SolsenS Offline
                                SolsenS Offline
                                Solsen
                                wrote on sidst redigeret af
                                #252

                                Fortsætter tendensen vil forsøget ikke få succes.

                                1 Reply Last reply
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                                • SolsenS Offline
                                  SolsenS Offline
                                  Solsen
                                  wrote on sidst redigeret af
                                  #253

                                  Styrker troen på at Acasunlimab kan blive spændende.

                                  1 Reply Last reply
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                                  • SolsenS Offline
                                    SolsenS Offline
                                    Solsen
                                    wrote on sidst redigeret af
                                    #254

                                    Biontech kan have valgt forkert da de op.out. på Acasunlimab, idet de også har lagt mange kræfter i deres VEGF/PD-2

                                    1 Reply Last reply
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                                    • SolsenS Offline
                                      SolsenS Offline
                                      Solsen
                                      wrote on sidst redigeret af
                                      #255

                                      https://investors.biontech.de/news-releases/news-release-details/biontech-acquire-biotheus-boost-oncology-strategy/ De lavede et køb i 2024 på det nævnte stof VEGF-A/PD-L1 på $800 mln.

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #256

                                        Tepezza (teprotumumab) received a positive opinion from the CHMP for the treatment of adults with moderate to severe Thyroid Eye Disease (TED), also known as Graves’ Eye Disease, a rare autoimmune disease that triggers inflammation of muscles, fat, and other tissues around and behind the eyes. Treatment options for moderate-to-severe TED are limited, most patients are treated with corticosteroids and some patients need multiple reconstructive surgeries

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #257

                                          https://www.ema.europa.eu/en/news/meeting-highlights-committee-medicinal-products-human-use-chmp-22-25-april-2025 - https://www.ema.europa.eu/en/medicines/human/EPAR/tepezza

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