Genmab — December 2024

[E_L]

Healthcare stocks fall as lawmakers push for bill to break up drug middlemen https://www.reuters.com/business/healthcare-pharmaceuticals/health-insurer-stocks-fall-wsj-says-lawmakers-set-break-up-pharmacy-benefit-2024-12-11/ https://www.cnbc.com/2024/12/11/health-care-stocks-fall-after-warren-pbm-bill-brian-thompson-shooting.html

[E_L]

may contribute to today's sector weakness, but i do not think this would negatively impact biotech firms (on the contrary)

[lahn1]

Nice call EL on the CLL, no breaking up middlemen, would be a good thing generally speaking.

[Aaanditsgone]

Nævnte de noget i går om, hvorfor beslutning om fremtiden for GEN1042 er blevet rykket til 2025?

[E_L]

i think that was already sort of clear from the Q3 call in Nov: JvdW: So for 1042, we are still collecting more data. And in the next months, we aim to take a decision on next steps. So we will be in the coming months, and we have collected all that data, different doses and dose frequency, we'll make a decision on next step for 1042 bispecific program.

[E_L]

and: On GEN1042, we are still collecting data in frontline settings in four different cancers, and we believe that we have all the data in hand in the coming months to make a decision on next steps, and we'll let you know at that time.

[lahn1]

Do we expect new approvals in EPCO beside JP 3L FL by 2026 ? Then 2L FL in 2027 and 2L and 1L DLBCL i 2028.

[E_L]

JP should be 1Q 2025

[E_L]

the rest will depend on how fast data comes, but they were very very optimistic (almost surprised) on the fast accruals
for the trials, no?

[E_L]

RBC: The top picks for 2025 European pharma/bio companies are Genmab, Almirall and Ipsen

[GeorgeBest]

Fra Nordea: “ Genmab (Hold) - Genmab var vært ved en R&D opdatering ifm. ASH konferencen. Ikke så meget nyt ift. data, men Genmab sagde, at de forventer at sende datatpakke til JNJ på Hexabody CD-38 inden årets udgang. Herefter starter uret og JNJ har 60 dage til at beslutte sig ift. udnyttelse af option. Vores bedste gæt er, at JnJ ikke udnytter optionen, da fremtidig fokus synes at være på bi-specifikke antistoffer og ikke mono-specifikke produkter som Hexabody CD-38.”

[E_L]

by the way, on GEN1042, i already wrote in my notes from the Q2 24 Biontech call 'delayed to 2025 ' it's not new.

[E_L]

what interest me more is if they can translate some of the findings from GEN1046, eg on dosing, to GEN1042, and if they are doing any work to that effect

[ProinvestorNEWS]

Helge Larsen indleder kort med en servicemeddelelse om ProInvestor.com, som har fået en større teknisk opdatering. Men ellers ser han i denne uge bl.a. på Genmab, som har fremlagt gode data på Epcoritamab på ASH-konferencen, Novo Nordisk og Cargrisema og på Bavarian Nordics aktietilbagekøb. Kort video: https://proinvestor.com/boards/123416

[Bella1]

Har købt i 1487, - det kan da kun gå fremad

[lahn1]

Er der nogen som har udregnet JnJ’s Darzalex net price ?

[JKY_VH]

Genmab er dagens aktie hos JB https://www.jyskebank.dk/finansnyt/morgennyt/5b01b76d-4e8b-4fe1-ba9e-3b8cad863ca5/!ut/p/z1/rVRNU-owFP0tLlh2kn7YFnelIGL5KoKk2TBpiTXapBhKFX-9KZ03rzL68I1kk9ybm3PO3LknAAMEsCAlS0nBckEyFUfYXk2NrqW7d3Dcn3ZMGM6HwfWsO9PnEwfcg6gDonYo3Z4HlqeqsbqG3ywPqvf4VEmkKJxvKSwdLEtGX8FC5JIr_XcV4iZhaxBdxlCPHXutWdSNNeuB6lpM2lQzYzcha9c2E3IJbk4xBPArhqU_WoWL3ky93RV8lRC-ISwVIOK5TKkQ-6K-4HTNdhxElBOW1altvpMJVZUqs6WyZCr4P81Hgt3pjQPtUWhZnXmgG7b1y5YcwU_CA7w-6AfGxDRM47zwx-22zw0_sKDtD4K5M55Be3JmeNfrtqH

[LP90]

ned ned og ned er der overhovedet ingen bund i aktien jeg kan ikke blive ved med at lave støtte opkøb

[The_Joker]

Det virker næsten som om Michael Novod's kommentarer endegyldigt at smadret alle forhåbninger om, at J&J kunne finde på at udnytte optionen. Jeg har fundet følgende beskrivelse af rettighederne fra en ældre artikel og jeg er nysgerrig efter, hvorvidt man virkelig skal betragte CD-38 værdiløst såfremt J&J ikke udnytter optionen https://www.genengnews.com/topics/cancer/janssen-genmab-partner-on-follow-on-to-darzalex-for-multiple-myeloma-diffuse-large-b-cell-lymphoma/

[The_Joker]

"If Janssen does not exercise its option, Genmab can continue to develop and commercialize HexaBody-CD38 for Darzalex-resistant patients, and in all other indications except those multiple myeloma or amyloidosis indications where Darzalex is either approved or is being actively developed."