Genmab — September 2024

[lahn1]

Jadretprotokol så

og formentligtæn

[lahn1]

Undskyld

[lahn1]

Ja og formentligt en også en nye protokoller omkring mitigation og discontinuation, som hvis det går som i Gen1046 vil give langt bedre resultater

[E_L]

'Genmab stock stabilized but faces uncertainties ahead' says Morgan Stanley https://za.investing.com/news/company-news/genmab-stock-stabilized-but-faces-uncertainties-ahead-says-morgan-stanley-93CH-3316303

[E_L]

Lymphoma Hub
@lymphomahub
CONGRESS | POSTER | #SOHO2024 | Daniel Kerr presents first results from the phase Ib/II EPCORE NHL-5 study investigating subcutaneous epcoritamab + pola-R-CHP as 1L treatment for #DLBCL (N=37). The ORR was 100% with CR 89%, demonstrating that epcoritamab can be combined with 1L SoC for DLBCL. https://x.com/lymphomahub/status/1831287376901013605/photo/1

[E_L]

difficult to read, but i don't need much more than ORR of 100% , CR 89% and no new safety signals

[E_L]

poster on glofitamab monotherapy in pts with R/R #DLBCL https://x.com/lymphomahub/status/1831291358440464845

[Bulder]

But probably not enough pts for a filing.

[E_L]

good point. How many do you think they need to go for a filing / Ph3 anyway? We don't know yet if these are all the patients that will be recruited in this arm, this is only first data, there may be more coming?

[E_L]

Lymphoma Hub
@lymphomahub
CONGRESS | POSTER | #SOHO2024 | Yasmin Karimi
@Yhkarimi
presents extended follow-up data beyond 2.5 years from the pivotal expansion cohort of the phase II EPCORE NHL-1 study of epcoritamab monotherapy in R/R #DLBCL (N=157). Of pts with a CR (n=65) 54% remained in CR at 30 months, with 69% PFS and 85% OS rates. https://x.com/lymphomahub/status/1831299262438641727

[Bulder]

Maybe Winkel will talk about it tonight.

[Sukkeralf]

maybe good for off-label sales

[Raun]

Vil nogen være sød og forklare mig. - Hvad hensigten kan være, når Morgan Stanley har brug for at gentage deres nedjustering af Genmab, bare ca. 14 dage efter nedjusteringen?

[gdn55]

For at tjene penge, der er mit bedste bud

[E_L]

The innovaTV 301 Trial for Patients with Cervical Cancer https://www.primrmed.com/cancer-education/the-innovatv-301-trial-for-patients-with-cervical-cancer

[Sukkeralf]

Jan var da i særdeles godt humør i dag

[Bulder]

Hørte det ikke. Noget interessant?

[kkjoel]

Han forklarede bl.a. om Superdaras virkningsmekanisme og gentog at den er super potent... og at han nok skulle hjælpe JNJ med at forstå det hvis de ikke selv kunne se det

[kkjoel]

Men der var selvfølgelig meget gentagelse.. og som Sukker siger var han i trashtalk-topform

[kkjoel]

Orker ikke - og kan ikke huske udenad - alt hvad han roste og fremhævede.. man må hellere læse transscriptet, som vel komme i morgen.