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  4. Genmab — Januar 2024

Genmab — Januar 2024

Planlagt Fastgjort Låst Flyttet Genmab
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  • S Offline
    S Offline
    Sukkeralf
    wrote on sidst redigeret af
    #1176

    Desuden sagde han jo også at der var en ny feature med deres CD3 arm, som de ikke havde offentliggjort endnu - måske den kan noget særligt. Desuden sagde han også at der var interesse fra aldrig selskaber, som så frem til at de første data offentliggøres i år.

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    • S Offline
      S Offline
      Sukkeralf
      wrote on sidst redigeret af
      #1177

      Drømmescenariet herfra lyder da gerne, at Genmab kommer med gode data og nu hvor de allerede er partner med Pfizer på Tivdag, så kunne det jo udvides til med B7H4 - Pfizer har jo allerede vist interesse i dette target - de har penge nok og er en stærk spiller - og Genmab får endnu et stor partner der sikre, at de ikke bliver opkøbt af nogen.

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      • L Offline
        L Offline
        LP90
        wrote on sidst redigeret af
        #1178

        Godmorgen 🙂

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        • S Offline
          S Offline
          Sukkeralf
          wrote on sidst redigeret af
          #1179

          Man skulle nok lige starte med en kop kaffe før man skriver......

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          • S Offline
            S Offline
            Sukkeralf
            wrote on sidst redigeret af
            #1180

            Et andet drømme scenarie er, at Genmab når at få data klar med HexaCD38 vs Darzalex FasPro til ASH - får en oral præsentation og viser at HexaCD er overlegen, så sætter de Janssen i en etisk svær position, når alle de sagkyndige får besked.

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #1181

              Kesimpta Q4 '23 (USD 641 million, +73% cc) sales grew across all regions driven by increased demand
              and strong access Full year 2023 $2171mn https://www.novartis.com/sites/novartis_com/files/q4-2023-media-release-en.pdf

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #1182

                and just repeating from earlier: Kesimpta Prefilled Pen Solution for injection had its annual US price change; +7 % early '23

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #1183

                  '24 sry

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                  • S Offline
                    S Offline
                    Sukkeralf
                    wrote on sidst redigeret af
                    #1184

                    Could come close to 3 billion USD this year - very nice indeed (only 17% increase)

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #1185

                      now i am still on my first coffee, but 17% to 3bn...?

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #1186

                        on B7H4 ; Pfizer bought a B7H4 ADC when they took over Seagen, so it must have been a strategic decision where they thought the ADC would be better.

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #1187

                          novartis q4-2023-investor-presentation https://www.novartis.com/sites/novartis_com/files/q4-2023-investor-presentation.pdf 'Kesimpta® FY sales doubled (USD 2.2bn) and on track for USD 4bn peak
                          based on compelling product profile'

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                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #1188

                            Ahh - it was Q4 sales * 4 and then * 1,17 to get to 3 billion.

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                            • S Offline
                              S Offline
                              Sukkeralf
                              wrote on sidst redigeret af
                              #1189

                              https://www.oncologypipeline.com/apexonco/esmo-2023-gsk-sets-pfizer-battle-b7-h4

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                              • S Offline
                                S Offline
                                Sukkeralf
                                wrote on sidst redigeret af
                                #1190

                                Regarding B7H4 still not a good sign if Pfizer chooses ADC over CD3.

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                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #1191

                                  So genmab royalty 1,5 bn dkk fy?

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                                  • H Offline
                                    H Offline
                                    Hen
                                    wrote on sidst redigeret af
                                    #1192

                                    Denne artikels indhold har vist ikke været oppe at vende? https://seekingalpha.com/news/4060348-jj-seeks-expanded-fda-approval-of-darzalex-faspro-for-multiple-myeloma?mailingid=34178580&messageid=2900&serial=34178580.9845&utm_campaign=rta-stock-news&utm_content=link-3&utm_medium=email&utm_source=seeking_alpha&utm_term=34178580.9845

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                                    • P Offline
                                      P Offline
                                      ProinvestorNEWS
                                      wrote on sidst redigeret af
                                      #1193

                                      Genmab-partner har stor vækst i Kesimpta-salget https://www.proinvestor.com/investornyt/1110393/genmab-partner-har-stor-vaekst-i-kesimpta-salget

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #1194

                                        @ 08.46 -it means at a minimum that they perceive their ADC to be better then their bispecific, but i don't think we have seen data on either, so not sure how high the bar has been set.... that PF-07260437 stopped recruiting isn't really news, we mentioned it here a few months ago

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #1195

                                          that is news @Hen , this is the same from JNJ https://www.jnj.com/johnson-johnson-submits-supplemental-biologics-license-application-to-u-s-fda-seeking-approval-of-darzalex-faspro-daratumumab-and-hyaluronidase-fihj-based-regimen-for-the-treatment-of-patients-with-transplant-eligible-newly-diagnosed-multiple-myeloma

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