Genmab — August 2023
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small new Dara trial; The goal of this clinical trial is to test the safety and tolerability of anti-CD38 monoclonal antibody (mAb), daratumumab, in combination with KRAS vaccine (Targovax TG-01/Stimulon QS-21) when given with anti-PD-1 (programmed cell death protein 1) mAb (nivolumab) in patients with advanced non-small cell lung cancer (NSCLC) or pancreatic ductal adenocarcinoma (PDAC). https://clinicaltrials.gov/study/NCT06015724?tab=table
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Endelig et indlæg idag
Tak for det, @EL. -
Kan ikke mindes nogen dag, overhovedet, hvor der har været så lidt trafik på PI’s chats….. Og det endda til trods for, at det faktisk blev en ret god børsdag.

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Jep

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Måske forventet, men dara var ikke på IRA drug listen https://www.hhs.gov/about/news/2023/08/29/hhs-selects-the-first-drugs-for-medicare-drug-price-negotiation.html
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Interessant. IRA drug listen vil blive fornyet årligt, så det kan jo være dara kommer med på et tidspunkt: "In future years, CMS will select for negotiation up to 15 more drugs covered under Part D for 2027, up to 15 more drugs for 2028 (including drugs covered under Part B and Part D), and up to 20 more drugs for each year after that, as outlined in the Inflation Reduction Act"
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J&J har 3 produkter på listen til prisforhandling, men listen er ikke noget der påvirker de pågældende firmaers aktiepris synderligt idag: https://www.statnews.com/2023/08/29/10-drugs-medicare-price-negotiation/
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New Genmab trial: A Phase 1/2a, Open-Label, Dose Escalation Trial of GEN3017 With Expansion Cohorts in Relapsed or Refractory CD30+ Classical Hodgkin Lymphoma and CD30+ Non-Hodgkin Lymphoma https://clinicaltrials.gov/study/NCT06018129
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Brief Summary:
The purpose of this trial is to evaluate the safety, tolerability, immunogenicity, pharmacokinetics (PK), pharmacodynamics (PD), and anti-tumor activity of GEN3017 as a monotherapy in participants with relapsed or refractory (R/R) CD30-expressing lymphomas.GEN3017 will be administered via subcutaneous injections
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Det var en dyr lukkeauktion idag

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Absolut - men lå i + på porteføljen kl. 16:55. - og endte i -0,18

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